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A ribosomally synthesised and post-translationally modified peptide containing a β-enamino acid and a macrocyclic motif

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dc.contributor.authorWang, Shan
dc.contributor.authorLin, Sixing
dc.contributor.authorFang, Qing
dc.contributor.authorGyampoh, Roland
dc.contributor.authorLu, Zhou
dc.contributor.authorGao, Yingli
dc.contributor.authorClarke, David J
dc.contributor.authorWu, Kewen
dc.contributor.authorTrembleau, Laurent
dc.contributor.authorYu, Yi
dc.contributor.authorKyeremeh, Kwaku
dc.contributor.authorMilne, Bruce F
dc.contributor.authorTabudravu, Jioji
dc.contributor.authorDeng, Hai
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.contributor.institutionUniversity of Aberdeen.Natural & Computing Sciencesen
dc.date.accessioned2022-08-30T15:29:01Z
dc.date.available2022-08-30T15:29:01Z
dc.date.issued2022-08-26
dc.descriptionAcknowledgements This work received financial support from Biotechnology and Biological Sciences Research Council UK (S.W. and H.D., BB/P00380X/1 and BB/R00479X/1, D.J.C., BB/R013993/1), Scottish Funding Council Covid-19 Grant extension and Bridging Fund (S.W. and H.D.); UKRI Covid-19 Extension Allocation Fund (S.W. and H.D.); The Elphinstone Scholarship of University of Aberdeen (QF), Leverhulme Trust-Royal Society Africa award (AA090088) and the jointly funded UK Medical Research Council UK Department for International Development (MRC/DFID) Concordat agreement African Research Leaders Award (MR/S00520X/1 to K.K. and H.D.), and National Natural Science Foundation of China (31570033, 31811530299, and 31870035 to Y.Y., 31929001 to H.D.), and the Royal Society-NSFC Newton Mobility Grant Award (IEC\NSFC\170617 to H.D. and Y.Y.). B.F.M. thanks the Portuguese Foundation for Science and Technology for financial support (POCI-01-0145-FEDER-032229 and CENTRO-01-0145-FEDER-000014, 2017-2020). H.D. and S.W. thank Professor Brady Moore in the Scripps Institute of Oceanography, University of San Diego, USA, for the gift of pCAP003 plasmid, Dr. Vladimir Larionov in National Cancer Institute, National Institute of Health, Bethesda, USA for the gift of Sacharomyces cerevisiae VL6-48N strain, Dr Juan-Pablo Gomez-Escribano and Professor Mervyn Bibb in John Innes Centre, UK for the gift of Streptomyces coelicolor M1152, and Samantha Law and Carol Philips in NCIMB Ltd (UK) for the kind gift of Streptomyces kurssanovii NCIMB12788en
dc.description.statusPeer revieweden
dc.format.extent15
dc.format.extent2541797
dc.identifier219058090
dc.identifier20fcc50d-72ef-4a1e-8661-c5d400cc6c6c
dc.identifier36028509
dc.identifier85136641461
dc.identifier.citationWang, S, Lin, S, Fang, Q, Gyampoh, R, Lu, Z, Gao, Y, Clarke, D J, Wu, K, Trembleau, L, Yu, Y, Kyeremeh, K, Milne, B F, Tabudravu, J & Deng, H 2022, 'A ribosomally synthesised and post-translationally modified peptide containing a β-enamino acid and a macrocyclic motif', Nature Communications, vol. 13, no. 1, 5044. https://doi.org/10.1038/s41467-022-32774-3en
dc.identifier.doi10.1038/s41467-022-32774-3
dc.identifier.issn2041-1723
dc.identifier.otherORCID: /0000-0001-6376-9077/work/118192010
dc.identifier.otherORCID: /0000-0002-5522-4808/work/118987600
dc.identifier.otherORCID: /0000-0002-0047-0622/work/159509069
dc.identifier.urihttps://hdl.handle.net/2164/19120
dc.language.isoeng
dc.relation.ispartofNature Communicationsen
dc.subjectSubstantive link via an eligible employment contracten
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subject2040 Health, Nutrition and Wellbeingen
dc.subjectBiochemistryen
dc.subjectBiosynthesisen
dc.subjectNatural productsen
dc.subjectPeptidesen
dc.subjectQD Chemistryen
dc.subjectUK Research and Innovation (UKRI)en
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/P00380X/1en
dc.subjectBB/R00479X/1en
dc.subjectBB/R013993/1)en
dc.subjectOtheren
dc.subjectAA090088en
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/S00520X/1en
dc.subjectSupplementary Dataen
dc.subject.lccQDen
dc.titleA ribosomally synthesised and post-translationally modified peptide containing a β-enamino acid and a macrocyclic motifen
dc.typeJournal articleen

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