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Glyoxylate cycle gene ICL1 is essential for the metabolic flexibility and virulence of Candida glabrata

dc.contributor.authorChew, Shu Yih
dc.contributor.authorHo, Kok Lian
dc.contributor.authorCheah, Yoke Kqueen
dc.contributor.authorNg, Tzu Shan
dc.contributor.authorSandai, Doblin
dc.contributor.authorBrown, Alistair J. P.
dc.contributor.authorLung, Leslie Than Thian
dc.contributor.institutionUniversity of Aberdeen.MRC Centre for Medical Mycologyen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2019-02-27T12:00:25Z
dc.date.available2019-02-27T12:00:25Z
dc.date.issued2019-02-26
dc.descriptionWe would like to acknowledge Professor Karl Kuchler from Medical University of Vienna for the kind gifts of C. glabrata strains used in this study. This study was funded by Fundamental Research Grant Scheme (FRGS) from Ministry of Education (MOE), Malaysia (Grant number: 01-01-14-1456FR). S.Y. is a recipient of the MyBrain 15 Scholarship from MOE, Malaysia. A.B. was supported by the Medical Research Council Centre for Medical Mycology at the University of Aberdeen (MR/N006364/1), by a programme grant from the UK Medical Research Council (MR/M026663/1), by a Strategic Award from the Wellcome Trust (097377) and by a grant from the UK Biotechnology and Biological Sciences Research Council (BB/P020119/1).en
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent2898888
dc.identifier141754285
dc.identifier2cd70d4f-1d9f-4652-8ae6-01ae29246f35
dc.identifier85062097147
dc.identifier30808979
dc.identifier000459702900012
dc.identifier.citationChew, S Y, Ho, K L, Cheah, Y K, Ng, T S, Sandai, D, Brown, A J P & Lung, L T T 2019, 'Glyoxylate cycle gene ICL1 is essential for the metabolic flexibility and virulence of Candida glabrata', Scientific Reports, vol. 9, no. 1, 2843, pp. 2843. https://doi.org/10.1038/s41598-019-39117-1en
dc.identifier.doi10.1038/s41598-019-39117-1
dc.identifier.iss1en
dc.identifier.issn2045-2322
dc.identifier.otherMendeley: 978f1db2-68e5-3d5d-ac48-770943d598fc
dc.identifier.urihttp://hdl.handle.net/2164/11968
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85062097147&partnerID=8YFLogxKen
dc.identifier.urlhttp://www.mendeley.com/research/glyoxylate-cycle-gene-icl1-essential-metabolic-flexibility-virulence-candida-glabrataen
dc.identifier.vol9en
dc.language.isoeng
dc.relation.ispartofScientific Reportsen
dc.subjectALBICANSen
dc.subjectASPERGILLUS-FUMIGATUSen
dc.subjectCARBON UTILIZATIONen
dc.subjectISOCITRATE LYASEen
dc.subjectMACROPHAGEen
dc.subjectPATHWAYSen
dc.subjectSURVIVALen
dc.subjectR Medicine (General)en
dc.subjectGeneralen
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/M026663/1en
dc.subjectMR/N006364/1en
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/P020119/1en
dc.subjectWellcome Trusten
dc.subject097377en
dc.subject.lccR1en
dc.titleGlyoxylate cycle gene ICL1 is essential for the metabolic flexibility and virulence of Candida glabrataen
dc.typeJournal articleen

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