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Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance

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dc.contributor.authorSwamy, Mahima
dc.contributor.authorAbeler-Dörner, Lucie
dc.contributor.authorChettle, James
dc.contributor.authorMahlakõiv, Tanel
dc.contributor.authorGoubau, Delphine
dc.contributor.authorChakravarty, Probir
dc.contributor.authorRamsay, George
dc.contributor.authorReis e Sousa, Caetano
dc.contributor.authorStaeheli, Peter
dc.contributor.authorBlacklaws, Barbara A
dc.contributor.authorHeeney, Jonathan L
dc.contributor.authorHayday, Adrian C
dc.date.accessioned2018-08-07T09:38:06Z
dc.date.available2018-08-07T09:38:06Z
dc.date.issued2015-05-19
dc.descriptionSupport was provided by the Wellcome Trust (A.C.H., J.L.H., G.R) and Cancer Research UK (A.C.H.), Department of Health via the National Institute for Health Research (NIHR) comprehensive Biomedical Research Centre award to Guy's & St Thomas' NHS Foundation Trust (L.A.-D.; A.C.H.); Marie Curie and EMBO fellowships (M.S.). We thank Professor D. Cantrell for generous support of M.S.; Dr D. Kaiserlien (Lyon) for the gift of MODE-K cells; Dr B. Spencer-Dene for histological stainings; Dr P. East for contributing to microarray data analysis, and our many colleagues for useful discussions and criticisms, particularly Dr V. Hornung. We acknowledge the staffs of the flow cytometry and animal care facilities of the Francis Crick Institute, Lincoln's Inn Fields Laboratories, London, UK, King’s College London, and the Universities of Freiburg, Cambridge, and Dundee.en
dc.description.statusPeer revieweden
dc.format.extent12
dc.format.extent1199111
dc.identifier130358104
dc.identifierf35081ae-f593-4426-b9d4-f96ebbb93403
dc.identifier25987506
dc.identifier84930226970
dc.identifier.citationSwamy, M, Abeler-Dörner, L, Chettle, J, Mahlakõiv, T, Goubau, D, Chakravarty, P, Ramsay, G, Reis e Sousa, C, Staeheli, P, Blacklaws, B A, Heeney, J L & Hayday, A C 2015, 'Intestinal intraepithelial lymphocyte activation promotes innate antiviral resistance', Nature Communications, vol. 6, 7090. https://doi.org/10.1038/ncomms8090en
dc.identifier.doi10.1038/ncomms8090
dc.identifier.issn2041-1723
dc.identifier.otherPubMedCentral: PMC4479038
dc.identifier.urihttp://hdl.handle.net/2164/10867
dc.identifier.vol6en
dc.language.isoeng
dc.relation.ispartofNature Communicationsen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectAnimalsen
dc.subjectCaliciviridae Infectionsen
dc.subjectCytokinesen
dc.subjectEpithelial Cellsen
dc.subjectFemaleen
dc.subjectGastroenteritisen
dc.subjectImmunity, Innateen
dc.subjectInterferon-alphaen
dc.subjectInterferon-gammaen
dc.subjectInterferonsen
dc.subjectIntestine, Smallen
dc.subjectLymphocyte Activationen
dc.subjectLymphocytesen
dc.subjectMacrophagesen
dc.subjectMiceen
dc.subjectMice, Inbred C57BLen
dc.subjectMice, Knockouten
dc.subjectNorovirusen
dc.subjectT-Lymphocytesen
dc.subjectJournal Articleen
dc.subjectResearch Support, Non-U.S. Gov'ten
dc.subjectR Medicineen
dc.subjectWellcome Trusten
dc.subjectCancer Research UKen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleIntestinal intraepithelial lymphocyte activation promotes innate antiviral resistanceen
dc.typeJournal articleen

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