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Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease

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dc.contributor.authorFrahm, Silke
dc.contributor.authorMelis, Valeria
dc.contributor.authorHorsley, David
dc.contributor.authorRickard, Janet
dc.contributor.authorRiedel, Gernot
dc.contributor.authorFadda, Paula
dc.contributor.authorScherma, Maria
dc.contributor.authorHarrington, Charles
dc.contributor.authorWischik, Claude
dc.contributor.authorTheuring, Franz
dc.contributor.authorSchwab, Karima
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2017-12-22T00:02:59Z
dc.date.available2017-12-22T00:02:59Z
dc.date.issued2018-02-26
dc.descriptionAcknowledgments: The authors acknowledge Mandy Magbagbeolu and Heide Lueck for excellent technical assistance and Anna Thoma for assistance in behavioural testing and maintenance of animals. This work was funded by TauRx Therapeutics Ltd., Singapore. C.R.H. and C.M.W. declare that they are officers in TauRx Therapeutics Ltd.en
dc.description.statusPeer revieweden
dc.format.extent16
dc.format.extent2515992
dc.identifier112329890
dc.identifier611b9a21-d786-41d2-88e7-fa1fef94e1ac
dc.identifier29180135
dc.identifier29180135
dc.identifier85035755746
dc.identifier.citationFrahm, S, Melis, V, Horsley, D, Rickard, J, Riedel, G, Fadda, P, Scherma, M, Harrington, C, Wischik, C, Theuring, F & Schwab, K 2018, 'Alpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's disease', Behavioural Brain Research, vol. 339, pp. 153-168. https://doi.org/10.1016/j.bbr.2017.11.025, https://doi.org/10.1016/j.bbr.2017.11.025en
dc.identifier.doi10.1016/j.bbr.2017.11.025
dc.identifier.issn0166-4328
dc.identifier.otherORCID: /0000-0001-7063-7136/work/96652485
dc.identifier.otherORCID: /0000-0003-2250-3920/work/47672870
dc.identifier.urihttp://hdl.handle.net/2164/9815
dc.identifier.vol339en
dc.language.isoeng
dc.relation.ispartofBehavioural Brain Researchen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectJournal Articleen
dc.subjectα-Synucleinen
dc.subjectprotein aggregationen
dc.subjectParkinson’s diseaseen
dc.subjectmotor dysfunctionen
dc.subjectglutamateen
dc.subjectR Medicineen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleAlpha-Synuclein transgenic mice, h-α-SynL62, display α-Syn aggregation and a dopaminergic phenotype reminiscent of Parkinson's diseaseen
dc.typeJournal articleen

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