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Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease

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dc.contributor.authorHarrington, Charles R
dc.contributor.authorStorey, John M D
dc.contributor.authorClunas, Scott
dc.contributor.authorHarrington, Kathleen A
dc.contributor.authorHorsley, David
dc.contributor.authorIshaq, Ahtsham
dc.contributor.authorKemp, Steven J
dc.contributor.authorLarch, Christopher P
dc.contributor.authorMarshall, Colin
dc.contributor.authorNicoll, Sarah L
dc.contributor.authorRickard, Janet E
dc.contributor.authorSimpson, Michael
dc.contributor.authorSinclair, James P
dc.contributor.authorStorey, Lynda J
dc.contributor.authorWischik, Claude M
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2015-05-28T13:59:03Z
dc.date.available2015-05-28T13:59:03Z
dc.date.issued2015-04-24
dc.descriptionCopyright © 2015, The American Society for Biochemistry and Molecular Biology. Acknowledgements-We thank Drs Timo Rager and Rolf Hilfiker (Solvias, Switzerland) for polymorph analyses.en
dc.description.statusPeer revieweden
dc.format.extent14
dc.format.extent3036793
dc.identifier49707206
dc.identifier55cb2b04-b245-45ac-b4b6-c9dfd2c706e3
dc.identifier25759392
dc.identifier84928401341
dc.identifier.citationHarrington, C R, Storey, J M D, Clunas, S, Harrington, K A, Horsley, D, Ishaq, A, Kemp, S J, Larch, C P, Marshall, C, Nicoll, S L, Rickard, J E, Simpson, M, Sinclair, J P, Storey, L J & Wischik, C M 2015, 'Cellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Disease', The Journal of Biological Chemistry, vol. 290, no. 17, pp. 10862-10875. https://doi.org/10.1074/jbc.M114.616029en
dc.identifier.doi10.1074/jbc.M114.616029
dc.identifier.iss17en
dc.identifier.issn0021-9258
dc.identifier.otherORCID: /0000-0002-5261-5467/work/73579095
dc.identifier.otherORCID: /0000-0003-2250-3920/work/47672881
dc.identifier.urihttp://hdl.handle.net/2164/4569
dc.identifier.vol290en
dc.language.isoeng
dc.relation.ispartofThe Journal of Biological Chemistryen
dc.subjectAlzheimer Diseaseen
dc.subjectcell biologyen
dc.subjectprotein aggregationen
dc.subjecttau protein (tau)en
dc.subjecttauopathyen
dc.subjectLMTXen
dc.subjectprion-like processingen
dc.subjectmethylthioniniumen
dc.subjectQH301 Biologyen
dc.subjectQD Chemistryen
dc.subject.lccQH301en
dc.subject.lccQDen
dc.titleCellular Models of Aggregation-Dependent Template-Directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer's Diseaseen
dc.typeJournal articleen

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