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TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells

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dc.contributor.authorDiamantopoulou, Zoi
dc.contributor.authorWhite, Gavin
dc.contributor.authorFadlullah, Muhammad Z H
dc.contributor.authorDreger, Marcel
dc.contributor.authorPickering, Karen
dc.contributor.authorMaltas, Joe
dc.contributor.authorAshton, Garry
dc.contributor.authorMacLeod, Ruth
dc.contributor.authorBaillie, George S.
dc.contributor.authorKouskoff, Valerie
dc.contributor.authorLacaud, Georges
dc.contributor.authorMurray, Graeme I
dc.contributor.authorSansom, Owen J.
dc.contributor.authorHurlstone, Adam F.L.
dc.contributor.authorMalliri, Angeliki
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2017-05-18T13:00:20Z
dc.date.available2017-05-18T13:00:20Z
dc.date.issued2017-05-08
dc.descriptionThis work was supported by MRC (grant number MR/L007495/1) and Cancer Research UK (grant number C5759/A12328) to A.M. We thank members of the Cell Signalling Group for helpful discussions and critical reading of the manuscript. We also thank the Molecular Biology Core Facility of CRUK Manchester Institute (CRUK MI) for performing next generation sequencing as well as the CRUK MI Computational Biology Group for preliminary bioinformatics analysis.en
dc.description.statusPeer revieweden
dc.format.extent21
dc.format.extent8671895
dc.identifier96523873
dc.identifier2af265c3-8b4f-44fe-9bda-f0c9546711db
dc.identifier85017453817
dc.identifier.citationDiamantopoulou, Z, White, G, Fadlullah, M Z H, Dreger, M, Pickering, K, Maltas, J, Ashton, G, MacLeod, R, Baillie, G S, Kouskoff, V, Lacaud, G, Murray, G I, Sansom, O J, Hurlstone, A F L & Malliri, A 2017, 'TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells', Cancer Cell, vol. 31, no. 5, pp. 621-634.e6. https://doi.org/10.1016/j.ccell.2017.03.007en
dc.identifier.doi10.1016/j.ccell.2017.03.007
dc.identifier.iss5en
dc.identifier.issn1535-6108
dc.identifier.otherORCID: /0000-0003-3981-2420/work/76973593
dc.identifier.urihttp://hdl.handle.net/2164/8649
dc.identifier.vol31en
dc.language.isoeng
dc.relation.ispartofCancer Cellen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectTIAM1en
dc.subjectTAZen
dc.subjectYAPen
dc.subjectWNTen
dc.subjectintestinal tumorigenesisen
dc.subjectcolorectal canceren
dc.subjectcell migrationen
dc.subjectinvasionen
dc.subjectmalignant progressionen
dc.subjectRC0254 Neoplasms. Tumors. Oncology (including Cancer)en
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/L007495/1en
dc.subjectCancer Research UKen
dc.subjectC5759/A12328en
dc.subjectSupplementary Dataen
dc.subject.lccRC0254en
dc.titleTIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cellsen
dc.typeJournal articleen

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