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HHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis

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dc.contributor.authorAravani, Dimitra
dc.contributor.authorMorris, Gavin E
dc.contributor.authorJones, Peter D
dc.contributor.authorTattersall, Helena K
dc.contributor.authorKaramanavi, Elisavet
dc.contributor.authorKaiser, Michael A
dc.contributor.authorKostogrys, Renata B
dc.contributor.authorGhaderi Najafabadi, Maryam
dc.contributor.authorAndrews, Sarah L
dc.contributor.authorNath, Mintu
dc.contributor.authorYe, Shu
dc.contributor.authorStringer, Emma J
dc.contributor.authorSamani, Nilesh J
dc.contributor.authorWebb, Tom R
dc.contributor.institutionUniversity of Aberdeen.Other Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Statisticsen
dc.date.accessioned2019-08-06T11:00:07Z
dc.date.available2019-08-06T11:00:07Z
dc.date.issued2019-08-06
dc.descriptionThe research leading to these results has received funding from the European Union Seventh Framework Programme FP7/2007–2013 under grant agreement number HEALTH-F2-2013–601456, a Transatlantic Networks of Excellence Award (12CVD02) from The Leducq Foundation and the British Heart Foundation (SP/18/8/33620) as a partner of the European Research Area Network on Cardiovascular Diseases (ERA-CVD) druggable-MI-genes (01KL1802) and supported by the UK National Institute for Health Research (NIHR) Leicester Biomedical Research Centre. Dr Samani is a UK NIHR Senior Investigator. Drs Morris, Ye, and Webb are funded by the British Heart Foundation (SP/16/4/32697).en
dc.description.statusPeer revieweden
dc.format.extent14
dc.format.extent1375719
dc.identifier145528258
dc.identifierbc0bf279-fb72-4f01-813d-2c8e9f60e9ea
dc.identifier31163988
dc.identifier000478747900014
dc.identifier85071063221
dc.identifier.citationAravani, D, Morris, G E, Jones, P D, Tattersall, H K, Karamanavi, E, Kaiser, M A, Kostogrys, R B, Ghaderi Najafabadi, M, Andrews, S L, Nath, M, Ye, S, Stringer, E J, Samani, N J & Webb, T R 2019, 'HHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosis', Circulation, vol. 140, no. 6, pp. 500–513. https://doi.org/10.1161/CIRCULATIONAHA.119.041059en
dc.identifier.doi10.1161/CIRCULATIONAHA.119.041059
dc.identifier.iss6en
dc.identifier.issn0009-7322
dc.identifier.otherMendeley: acf3aeee-b430-3283-860b-fdc58d9658eb
dc.identifier.otherORCID: /0000-0002-0753-0464/work/161797570
dc.identifier.urihttp://hdl.handle.net/2164/12682
dc.identifier.urlhttp://www.mendeley.com/research/hhipl1-gene-14q32-coronary-artery-disease-locus-positively-regulates-hedgehog-signaling-promotes-athen
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85071063221&partnerID=8YFLogxKen
dc.identifier.urlhttps://www.ahajournals.org/doi/suppl/10.1161/circulationaha.119.041059en
dc.identifier.vol140en
dc.language.isoeng
dc.relation.ispartofCirculationen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectatherosclerosisen
dc.subjectcoronary artery diseaseen
dc.subjectgenome-wide association studyen
dc.subjecthedgehogsen
dc.subjectsignalingen
dc.subjectMIGRATIONen
dc.subjectACTIVATIONen
dc.subjectVESSELen
dc.subjectPROTEINen
dc.subjectANGIOGENESISen
dc.subjectSONIC HEDGEHOGen
dc.subjectMUSCLE-CELL PROLIFERATIONen
dc.subjectINDUCTIONen
dc.subjectPATHWAYen
dc.subjectEXPRESSIONen
dc.subjectR Medicineen
dc.subjectCardiology and Cardiovascular Medicineen
dc.subjectPhysiology (medical)en
dc.subjectBritish Heart Foundationen
dc.subjectSP/18/8/33620en
dc.subjectSP/16/4/32697en
dc.subject.lccRen
dc.titleHHIPL1, a Gene at the 14q32 Coronary Artery Disease Locus, Positively Regulates Hedgehog Signaling and Promotes Atherosclerosisen
dc.typeJournal articleen

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