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Compression stockings in addition to low-molecular-weight heparin to prevent venous thromboembolism in surgical inpatients requiring pharmacoprophylaxis : the GAPS non-inferiority RCT

dc.contributor.authorShalhoub, Joseph
dc.contributor.authorLawton, Rebecca
dc.contributor.authorHudson, Jemma
dc.contributor.authorBaker, Christopher
dc.contributor.authorBradbury, Andrew
dc.contributor.authorDhillon, Karen
dc.contributor.authorEverington, Tamara
dc.contributor.authorGohel, Manjit S
dc.contributor.authorHamady, Zaed
dc.contributor.authorHunt, Beverly J
dc.contributor.authorStansby, Gerard
dc.contributor.authorWarwick, David
dc.contributor.authorNorrie, John
dc.contributor.authorDavies, Alun H
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Evaluationen
dc.date.accessioned2020-12-10T17:16:00Z
dc.date.available2020-12-10T17:16:00Z
dc.date.issued2020-12-01
dc.descriptionFunding: This project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme and will be published in full in Health Technology Assessment; Vol. 24, No. 69. See the NIHR Journals Library website for further project information. Acknowledgements: Trial Management Group The Trial Management Group comprised Professor Alun Davies (as chief investigator), Ms Rebecca Lawton (as trial manager), Ms Jemma Hudson (as statistician) and Professor John Norrie (as senior statistician). The Centre for Healthcare Randomised Trials The following members were part of the wider CHaRT study team: Alison MacDonald (senior trial manager), Mr Mark Forrest (senior IT development manager) and Dr Samantha Wileman (quality assurance manager). Department of Surgery and Cancer, Imperial College London The following members were part of the wider GAPS trial team: Francine Heatley (trial manager), Becky Ward (sponsor), Matt Ryan (research manager), and Kirti Patel and Jayne Alderson (contracts). Trial Steering Committee We would like to thank Professor Robert Hinchliffe (chairperson, clinical professor of vascular surgery), Dr Peter MacCallum (senior lecturer in haematology), Mr Nick Hickey (consultant vascular surgeon) and Dr Stephen Gerry (medical statistician and NIHR doctoral research fellow), and Ms Annya Stephens–Boal [lay member, Thrombosis UK (Llanwrda)], who provided invaluable input and advice as the independent lay member over the course of the study. Data Monitoring Committee The team would also like to thank the iDMC members, Mr Richard Bulbulia (chairperson, consultantvascular surgeon), Dr Adam Rye (consultant haematologist) and Professor Jonathan Emberson (associate professor, medical statistics and epidemiology) for their support and guidance. Patient and public involvement Annya Stephens–Boal was involved in the original design during the grant application stages and was an active member of the Trial Steering Committee throughout the study. Annya’s involvement is detailed in the patient and public involvement (PPI) lay person description (see Appendices 1 and 4). Data cleaning Data cleaning was performed by the trial manager and study statistician.en
dc.description.statusPeer revieweden
dc.format.extent80
dc.format.extent2820452
dc.identifier183027635
dc.identifierbd350b36-b2d3-4f13-87dc-6cff31c2661a
dc.identifier33275096
dc.identifier85097310587
dc.identifier000596449600001
dc.identifier.citationShalhoub, J, Lawton, R, Hudson, J, Baker, C, Bradbury, A, Dhillon, K, Everington, T, Gohel, M S, Hamady, Z, Hunt, B J, Stansby, G, Warwick, D, Norrie, J & Davies, A H 2020, 'Compression stockings in addition to low-molecular-weight heparin to prevent venous thromboembolism in surgical inpatients requiring pharmacoprophylaxis : the GAPS non-inferiority RCT', Health technology assessment (Winchester, England), vol. 24, no. 69, pp. 1-80. https://doi.org/10.3310/hta24690en
dc.identifier.doi10.3310/hta24690
dc.identifier.iss69en
dc.identifier.issn1366-5278
dc.identifier.urihttps://hdl.handle.net/2164/15496
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85097310587&partnerID=8YFLogxKen
dc.identifier.vol24en
dc.language.isoeng
dc.relation.ispartofHealth technology assessment (Winchester, England)en
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectGRADUATED COMPRESSION STOCKINGSen
dc.subjectLOW-MOLECULAR-WEIGHT HEPARINen
dc.subjectNON-INFERIORITYen
dc.subjectRISK ASSESSMENTen
dc.subjectSURGERYen
dc.subjectVENOUS THROMBOEMBOLISMen
dc.subjectR Medicineen
dc.subjectHealth Policyen
dc.subjectNational Institute for Health Research (NIHR)en
dc.subject.lccRen
dc.titleCompression stockings in addition to low-molecular-weight heparin to prevent venous thromboembolism in surgical inpatients requiring pharmacoprophylaxis : the GAPS non-inferiority RCTen
dc.typeJournal articleen

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