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Deciphering the genetic and epidemiological landscape of mitochondrial DNA abundance

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dc.contributor.authorHägg, Sara
dc.contributor.authorJylhävä, Juulia
dc.contributor.authorWang, Yunzhang
dc.contributor.authorCzene, Kamila
dc.contributor.authorGrassmann, Felix
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2021-06-08T11:39:01Z
dc.date.available2021-06-08T11:39:01Z
dc.date.issued2021-06
dc.descriptionAcknowledgements: The computations and data handling were enabled by resources provided by the Swedish National Infrastructure for Computing (SNIC) at UPPMAX, Uppsala University, partially funded by the Swedish Research Council through grant agreement no. 2018-05973. This research has been conducted using the UK Biobank Resource under Application Number 22224. Funding: Open Access funding provided by Karolinska Institute. Open Access funding provided by Karolinska Institute. This work was financed by the Swedish Research Council (Grant 2018-02547, 2015-03255, 2019-01272, 2018-02077), the Swedish Cancer Society (Grants CAN 2016/684), the Stockholm County Council (Grant no. 20170088), the Karolinska Institutet’s Research Foundation (Grant 2018-02146), Karolinska Institutet’s Strategic Research Program in Epidemiology, King Gustaf V:s and Queen Victoria's Foundation of Freemasons, and the Åke Wibergs Foundation (M19-0294). FG was a Leopoldina Postdoctoral Fellow (Grant no. LPDS 2018-06) funded by the Academy of Sciences Leopoldina. Correction to: Deciphering the genetic and epidemiological landscape of mitochondrial DNA abundance (Human Genetics, (2020), 10.1007/s00439-020-02249-w) The data were exclusively retrieved from the UK Biobank and can be accessed upon request from the UK Biobank. The mitochondrial DNA abundance as computed in this manuscript will be reported back to the UK Biobank upon publication. The scripts to compute the weights and the weighted mtDNA abundance in the UKB dataset will be published at https://github.com/GrassmannLab/MT_UKB.en
dc.description.statusPeer revieweden
dc.format.extent13
dc.format.extent2851157
dc.identifier191213866
dc.identifieracf03a82-2ed6-4d14-9f47-bdfb5019ef20
dc.identifier33385171
dc.identifier33547498
dc.identifier85098505254
dc.identifier85100562030
dc.identifier.citationHägg, S, Jylhävä, J, Wang, Y, Czene, K & Grassmann, F 2021, 'Deciphering the genetic and epidemiological landscape of mitochondrial DNA abundance', Human Genetics, vol. 140, pp. 849-861. https://doi.org/10.1007/s00439-020-02249-wen
dc.identifier.doi10.1007/s00439-020-02249-w
dc.identifier.issn0340-6717
dc.identifier.otherJisc: 50ea5e23a3714de4969ae69c5bbdc741
dc.identifier.otherORCID: /0000-0003-1390-7528/work/95223152
dc.identifier.urihttps://hdl.handle.net/2164/16647
dc.identifier.urlhttps://link.springer.com/article/10.1007/s00439-021-02258-3en
dc.identifier.vol140en
dc.language.isoeng
dc.relation.ispartofHuman Geneticsen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectOriginal Investigationen
dc.subjectR Medicineen
dc.subjectSupplementary Informationen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleDeciphering the genetic and epidemiological landscape of mitochondrial DNA abundanceen
dc.typeJournal articleen

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