Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia
| dc.contributor.author | Lemke, Nora | |
| dc.contributor.author | Melis, Valeria | |
| dc.contributor.author | Lauer, Dilyara | |
| dc.contributor.author | Magbagbeolu, Mandy | |
| dc.contributor.author | Neumann, Boris | |
| dc.contributor.author | Harrington, Charles R | |
| dc.contributor.author | Riedel, Gernot | |
| dc.contributor.author | Wischik, Claude M. | |
| dc.contributor.author | Theuring, Franz | |
| dc.contributor.author | Schwab, Karima | |
| dc.contributor.institution | University of Aberdeen.Medical Sciences | en |
| dc.contributor.institution | University of Aberdeen.Applied Medicine | en |
| dc.date.accessioned | 2020-11-03T09:41:01Z | |
| dc.date.available | 2020-11-03T09:41:01Z | |
| dc.date.issued | 2020-12-25 | |
| dc.description | Funding Information: Funding and additional information—This work was supported by EMPIR programme in Research Project 15HLT02 ReMiND cofinanced by the Participating States and the European Union's Horizon 2020 research and innovation programme (to N. L.). Work was also supported by WisTa Laboratories Ltd. (to V. M., D. L., M. M., C. R. H., G. R., C. M. W., F. T., and K. S.). Conflict of interest—This work was sponsored by WisTa Laboratories Ltd., an affiliate of TauRx Therapeutics Ltd. C. R. H. and C. M. W. are employees and officers of TauRx Therapeutics Ltd. | en |
| dc.description.status | Peer reviewed | en |
| dc.format.extent | 16 | |
| dc.format.extent | 3409447 | |
| dc.identifier | 178981139 | |
| dc.identifier | 807fd2c7-7dbe-4a0f-9503-10fdff1e89d9 | |
| dc.identifier | 33127647 | |
| dc.identifier | 85098333503 | |
| dc.identifier | 33453851 | |
| dc.identifier | 000603645900047 | |
| dc.identifier.citation | Lemke, N, Melis, V, Lauer, D, Magbagbeolu, M, Neumann, B, Harrington, C R, Riedel, G, Wischik, C M, Theuring, F & Schwab, K 2020, 'Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia', Journal of Biological Chemistry, vol. 295, no. 52, pp. 18508-18523. https://doi.org/10.1074/jbc.RA120.014890 | en |
| dc.identifier.doi | 10.1074/jbc.RA120.014890 | |
| dc.identifier.iss | 52 | en |
| dc.identifier.issn | 0021-9258 | |
| dc.identifier.other | Bibtex: Lemke30102020 | |
| dc.identifier.other | ORCID: 0000-0003-2250-3920 | |
| dc.identifier.other | ORCID: 0000-0001-7063-7136 | |
| dc.identifier.other | ORCID: /0000-0001-7063-7136/work/96652484 | |
| dc.identifier.other | ORCID: /0000-0003-2250-3920/work/173415875 | |
| dc.identifier.uri | https://hdl.handle.net/2164/15308 | |
| dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85098333503&partnerID=8YFLogxK | en |
| dc.identifier.url | https://massive.ucsd.edu/ProteoSAFe/static/massive.jsp | en |
| dc.identifier.url | http://www.jbc.org/content/early/2020/10/30/jbc.RA120.014890.abstract | en |
| dc.identifier.vol | 295 | en |
| dc.language.iso | eng | |
| dc.relation.ispartof | Journal of Biological Chemistry | en |
| dc.subject | SDG 3 - Good Health and Well-being | en |
| dc.subject | QD Chemistry | en |
| dc.subject | Molecular Biology | en |
| dc.subject | Biochemistry | en |
| dc.subject | Cell Biology | en |
| dc.subject | Other | en |
| dc.subject | Supplementary Data | en |
| dc.subject.lcc | QD | en |
| dc.title | Differential compartmental processing and phosphorylation of pathogenic human tau and native mouse tau in the Line 66 model of frontotemporal dementia | en |
| dc.type | Journal article | en |
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