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Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for Candida albicans Cell Wall Maintenance

dc.contributor.authorLiu, Ning Ning
dc.contributor.authorAcosta-Zaldívar, Maikel
dc.contributor.authorQi, Wanjun
dc.contributor.authorDiray-Arce, Joann
dc.contributor.authorWalker, Louise A.
dc.contributor.authorKottom, Theodore J.
dc.contributor.authorKelly, Rachel
dc.contributor.authorYuan, Min
dc.contributor.authorAsara, John M.
dc.contributor.authorLasky-Su, Jessica Ann
dc.contributor.authorLevy, Ofer
dc.contributor.authorLimper, Andrew H.
dc.contributor.authorGow, Neil A.R.
dc.contributor.authorKöhler, Julia R.
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2020-04-14T16:00:02Z
dc.date.available2020-04-14T16:00:02Z
dc.date.issued2020-03-17
dc.descriptionACKNOWLEDGMENTS We declare no conflicts of interest. We thank Jesús Pla for his kind gift of the anti-Mkc1 antibody and Kristin Moffitt and Richard Malley for generous advice in ELISA technology and use of the ELISA reader. We thank Tahmeena Chowdhury for scientific discussions leading up to this work. We thank the Candida Genome Database. N.-N.L., M.A.-Z., W.Q., and J.R.K. were supported by R21 AI137716 and by Boston Children’s Hospital Department of Pediatrics. M.A.-Z. was partially funded by the Alfonso Martin Escudero Foundation. J.D.-A. and O.L. were funded by the Boston Children’s Hospital Department of Pediatrics and U19 AI118608-01A1. N.A.R.G. was supported by the Wellcome Trust and the Medical Research Council Centre for Medical Mycology (MR/N006364/1).en
dc.description.statusPeer revieweden
dc.format.extent19
dc.format.extent3553818
dc.identifier160302336
dc.identifier8b87b8be-a982-4956-8055-b5d5bed3f3be
dc.identifier85082082930
dc.identifier32184254
dc.identifier000531071300071
dc.identifier.citationLiu, N N, Acosta-Zaldívar, M, Qi, W, Diray-Arce, J, Walker, L A, Kottom, T J, Kelly, R, Yuan, M, Asara, J M, Lasky-Su, J A, Levy, O, Limper, A H, Gow, N A R & Köhler, J R 2020, 'Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for Candida albicans Cell Wall Maintenance', mBio, vol. 11, no. 2, e03225-19. https://doi.org/10.1128/mBio.03225-19en
dc.identifier.doi10.1128/mBio.03225-19
dc.identifier.iss2en
dc.identifier.issn2161-2129
dc.identifier.urihttps://hdl.handle.net/2164/14070
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85082082930&partnerID=8YFLogxKen
dc.identifier.vol11en
dc.language.isoeng
dc.relation.ispartofmBioen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectantifungal agentsen
dc.subjectCandida albicansen
dc.subjectcell wallen
dc.subjectchitin synthaseen
dc.subjectglucan synthaseen
dc.subjectnucleotide sugaren
dc.subjectPho84en
dc.subjectphosphate metabolismen
dc.subjectNIKKOMYCIN-Zen
dc.subjectBETA-GLUCANen
dc.subjectMECHANISMen
dc.subjectSACCHAROMYCES-CEREVISIAEen
dc.subjectCHITIN SYNTHASE GENEen
dc.subjectMEMBRANE PHOSPHOLIPIDSen
dc.subjectINTEGRITYen
dc.subjectIN-VIVOen
dc.subjectGROWTHen
dc.subjectARCHITECTUREen
dc.subjectAntifungal agentsen
dc.subjectNucleotide sugaren
dc.subjectChitin synthaseen
dc.subjectCell wallen
dc.subjectGlucan synthaseen
dc.subjectPhosphate metabolismen
dc.subjectQR Microbiologyen
dc.subjectVirologyen
dc.subjectMicrobiologyen
dc.subjectMedical Research Council (MRC)en
dc.subjectCentre for Medical Mycologyen
dc.subject(MR/N006364/1)en
dc.subjectWellcome Trusten
dc.subject.lccQRen
dc.titlePhosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for Candida albicans Cell Wall Maintenanceen
dc.typeJournal articleen

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