Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for Candida albicans Cell Wall Maintenance
| dc.contributor.author | Liu, Ning Ning | |
| dc.contributor.author | Acosta-Zaldívar, Maikel | |
| dc.contributor.author | Qi, Wanjun | |
| dc.contributor.author | Diray-Arce, Joann | |
| dc.contributor.author | Walker, Louise A. | |
| dc.contributor.author | Kottom, Theodore J. | |
| dc.contributor.author | Kelly, Rachel | |
| dc.contributor.author | Yuan, Min | |
| dc.contributor.author | Asara, John M. | |
| dc.contributor.author | Lasky-Su, Jessica Ann | |
| dc.contributor.author | Levy, Ofer | |
| dc.contributor.author | Limper, Andrew H. | |
| dc.contributor.author | Gow, Neil A.R. | |
| dc.contributor.author | Köhler, Julia R. | |
| dc.contributor.institution | University of Aberdeen.Medicine, Medical Sciences & Nutrition | en |
| dc.contributor.institution | University of Aberdeen.Applied Medicine | en |
| dc.date.accessioned | 2020-04-14T16:00:02Z | |
| dc.date.available | 2020-04-14T16:00:02Z | |
| dc.date.issued | 2020-03-17 | |
| dc.description | ACKNOWLEDGMENTS We declare no conflicts of interest. We thank Jesús Pla for his kind gift of the anti-Mkc1 antibody and Kristin Moffitt and Richard Malley for generous advice in ELISA technology and use of the ELISA reader. We thank Tahmeena Chowdhury for scientific discussions leading up to this work. We thank the Candida Genome Database. N.-N.L., M.A.-Z., W.Q., and J.R.K. were supported by R21 AI137716 and by Boston Children’s Hospital Department of Pediatrics. M.A.-Z. was partially funded by the Alfonso Martin Escudero Foundation. J.D.-A. and O.L. were funded by the Boston Children’s Hospital Department of Pediatrics and U19 AI118608-01A1. N.A.R.G. was supported by the Wellcome Trust and the Medical Research Council Centre for Medical Mycology (MR/N006364/1). | en |
| dc.description.status | Peer reviewed | en |
| dc.format.extent | 19 | |
| dc.format.extent | 3553818 | |
| dc.identifier | 160302336 | |
| dc.identifier | 8b87b8be-a982-4956-8055-b5d5bed3f3be | |
| dc.identifier | 85082082930 | |
| dc.identifier | 32184254 | |
| dc.identifier | 000531071300071 | |
| dc.identifier.citation | Liu, N N, Acosta-Zaldívar, M, Qi, W, Diray-Arce, J, Walker, L A, Kottom, T J, Kelly, R, Yuan, M, Asara, J M, Lasky-Su, J A, Levy, O, Limper, A H, Gow, N A R & Köhler, J R 2020, 'Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for Candida albicans Cell Wall Maintenance', mBio, vol. 11, no. 2, e03225-19. https://doi.org/10.1128/mBio.03225-19 | en |
| dc.identifier.doi | 10.1128/mBio.03225-19 | |
| dc.identifier.iss | 2 | en |
| dc.identifier.issn | 2161-2129 | |
| dc.identifier.uri | https://hdl.handle.net/2164/14070 | |
| dc.identifier.url | http://www.scopus.com/inward/record.url?scp=85082082930&partnerID=8YFLogxK | en |
| dc.identifier.vol | 11 | en |
| dc.language.iso | eng | |
| dc.relation.ispartof | mBio | en |
| dc.subject | SDG 3 - Good Health and Well-being | en |
| dc.subject | antifungal agents | en |
| dc.subject | Candida albicans | en |
| dc.subject | cell wall | en |
| dc.subject | chitin synthase | en |
| dc.subject | glucan synthase | en |
| dc.subject | nucleotide sugar | en |
| dc.subject | Pho84 | en |
| dc.subject | phosphate metabolism | en |
| dc.subject | NIKKOMYCIN-Z | en |
| dc.subject | BETA-GLUCAN | en |
| dc.subject | MECHANISM | en |
| dc.subject | SACCHAROMYCES-CEREVISIAE | en |
| dc.subject | CHITIN SYNTHASE GENE | en |
| dc.subject | MEMBRANE PHOSPHOLIPIDS | en |
| dc.subject | INTEGRITY | en |
| dc.subject | IN-VIVO | en |
| dc.subject | GROWTH | en |
| dc.subject | ARCHITECTURE | en |
| dc.subject | Antifungal agents | en |
| dc.subject | Nucleotide sugar | en |
| dc.subject | Chitin synthase | en |
| dc.subject | Cell wall | en |
| dc.subject | Glucan synthase | en |
| dc.subject | Phosphate metabolism | en |
| dc.subject | QR Microbiology | en |
| dc.subject | Virology | en |
| dc.subject | Microbiology | en |
| dc.subject | Medical Research Council (MRC) | en |
| dc.subject | Centre for Medical Mycology | en |
| dc.subject | (MR/N006364/1) | en |
| dc.subject | Wellcome Trust | en |
| dc.subject.lcc | QR | en |
| dc.title | Phosphoric Metabolites Link Phosphate Import and Polysaccharide Biosynthesis for Candida albicans Cell Wall Maintenance | en |
| dc.type | Journal article | en |
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