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Structure‐based design, synthesis and bioactivity of a new anti‐TNFα cyclopeptide

dc.contributor.authorIdress, Mohannad
dc.contributor.authorMilne, Bruce F.
dc.contributor.authorThompson, Gary S.
dc.contributor.authorTrembleau, Laurent
dc.contributor.authorJaspars, Marcel
dc.contributor.authorHoussen, Wael E
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2020-03-06T14:45:01Z
dc.date.available2020-03-06T14:45:01Z
dc.date.issued2020-02-19
dc.descriptionThis project was supported by grants from the University of Aberdeen (Elphinstone PhD scholarship, M.I.), ERC (No. 339367, M.J.), EPSRC fellowship (EP/S027246/1, W.E.H.). B.F.M. funded by the Portuguese Fundação para a Ciência e a Tecnologia (projects CENTRO-01- 0145-FEDER-000014, 2017-2020 and POCI-01-0145-FEDER-032229) and the Donostia International Physics Centre (San Sebastián, Spain). The Coimbra Chemistry Centre is supported by the Fundação para a Ciência e a Tecnologia, through the Project PEstOE/QUI/UI0313/2014 and POCI-01-0145-FEDER-007630.en
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent1827142
dc.identifier157418707
dc.identifiera5cb7704-aacc-4e7a-8569-8c6cf46dd677
dc.identifier85079850811
dc.identifier000522454500158
dc.identifier.citationIdress, M, Milne, B F, Thompson, G S, Trembleau, L, Jaspars, M & Houssen, W E 2020, 'Structure‐based design, synthesis and bioactivity of a new anti‐TNFα cyclopeptide', Molecules, vol. 25, no. 4, 922. https://doi.org/10.3390/molecules25040922, https://doi.org/10.3390/molecules25040922en
dc.identifier.doi10.3390/molecules25040922
dc.identifier.iss4en
dc.identifier.issn1420-3049
dc.identifier.otherBibtex: molecules25040922
dc.identifier.otherORCID: /0000-0001-6376-9077/work/72631835
dc.identifier.otherBibtex: molecules25040922
dc.identifier.otherORCID: /0000-0002-5522-4808/work/119414194
dc.identifier.otherORCID: /0000-0002-2426-6028/work/163664303
dc.identifier.urihttps://hdl.handle.net/2164/13833
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85079850811&partnerID=8YFLogxKen
dc.identifier.urlhttps://www.mdpi.com/1420-3049/25/4/922en
dc.identifier.vol25en
dc.language.isoeng
dc.relation.ispartofMoleculesen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectCyclic Peptidesen
dc.subjectNMR Structureen
dc.subjectDrug Designen
dc.subjectProtein‐Protein Interactionen
dc.subjectNMR structureen
dc.subjectProtein-protein interactionen
dc.subjectCyclic peptidesen
dc.subjectDrug designen
dc.subjectdrug designen
dc.subjectRECEPTORen
dc.subjectNECROSIS-FACTOR-ALPHAen
dc.subjectcyclic peptidesen
dc.subjectPEPTIDOMIMETICSen
dc.subjectINHIBITIONen
dc.subjectLIGANDSen
dc.subjectprotein-protein interactionen
dc.subjectINFLIXIMABen
dc.subjectEXPRESSIONen
dc.subjectBINDINGen
dc.subjectR Medicineen
dc.subjectDrug Discoveryen
dc.subjectAnalytical Chemistryen
dc.subjectChemistry (miscellaneous)en
dc.subjectMolecular Medicineen
dc.subjectPhysical and Theoretical Chemistryen
dc.subjectPharmaceutical Scienceen
dc.subjectOrganic Chemistryen
dc.subjectEngineering and Physical Sciences Research Council (EPSRC)en
dc.subjectEP/S027246/1en
dc.subjectEuropean Research Councilen
dc.subject339367en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleStructure‐based design, synthesis and bioactivity of a new anti‐TNFα cyclopeptideen
dc.typeJournal articleen

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