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VEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels

dc.contributor.authorErskine, Lynda
dc.contributor.authorFrancois, Urielle
dc.contributor.authorDenti, Laura
dc.contributor.authorJoyce, Andy
dc.contributor.authorTillo, Miguel
dc.contributor.authorBruce, Freyja
dc.contributor.authorVargesson, Neil
dc.contributor.authorRuhrberg, Christiana
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cell, Developmental and Cancer Biologyen
dc.date.accessioned2017-07-17T11:00:21Z
dc.date.available2017-07-17T11:00:21Z
dc.date.issued2017-07-04
dc.descriptionWe thank Vann Bennett and Daizing Zhou (Department of Biochemistry, Duke University Medical Center) for the design and generation of the Brn3bCre knock-in mice. We are grateful to Bennett Alakakone and Susan Reijntjes for help with preliminary experiments and to Anastasia Lampropoulou for preparing tissue culture media. We thank the staff of the Biological Resource Unit at the UCL Institute of Ophthalmology and the University of Aberdeen Institute of Medical Sciences Microscopy and Histology Facility and Medical Research Facility for technical assistance. Funding This research was funded by project grants from the Wellcome Trust [085476/A/08/Z to L.E., C.R.] and Biotechnology and Biological Sciences Research Council (BBSRC) [BB/J00815X/1 to L.E.; BB/J00930X/1 to C.R.] and a Wellcome Trust PhD Fellowship [092839/Z/10/Z to M.T.]. Deposited in PMC for immediate release.en
dc.description.statusPeer revieweden
dc.format.extent13
dc.format.extent17990585
dc.identifier101304816
dc.identifier22b995c1-4dde-4a2f-a23e-57be43ee094c
dc.identifier85021766340
dc.identifier.citationErskine, L, Francois, U, Denti, L, Joyce, A, Tillo, M, Bruce, F, Vargesson, N & Ruhrberg, C 2017, 'VEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vessels', Development, vol. 144, no. 13, pp. 2504-2516. https://doi.org/10.1242/dev.151621en
dc.identifier.doi10.1242/dev.151621
dc.identifier.iss13en
dc.identifier.issn0950-1991
dc.identifier.otherORCID: /0000-0001-6538-9406/work/145268361
dc.identifier.otherORCID: /0000-0001-8027-114X/work/145270794
dc.identifier.urihttp://hdl.handle.net/2164/8961
dc.identifier.vol144en
dc.language.isoeng
dc.relation.ispartofDevelopmenten
dc.subjectretinal ganglion cellen
dc.subjectoptic chiasmen
dc.subjectblood vesselen
dc.subjectaxon guidanceen
dc.subjectVEGF-Aen
dc.subjectR Medicineen
dc.subjectWellcome Trusten
dc.subject085476/A/08/Zen
dc.subject092839/Z/10/Zen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/J00815X/1en
dc.subjectBB/J00930X/1en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleVEGF-A and neuropilin 1 (NRP1) shape axon projections in the developing CNS via dual roles in neurons and blood vesselsen
dc.typeJournal articleen

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