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Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins

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dc.contributor.authorParkinson, James E
dc.contributor.authorTompkins, Hannah E.
dc.contributor.authorChakraborty, Amlan
dc.contributor.authorBurgess, Matthew
dc.contributor.authorDodd, Rebecca J.
dc.contributor.authorAdamson, Antony
dc.contributor.authorMacDonald, Andrew
dc.contributor.authorGibbs, Julie E.
dc.contributor.authorDurrington, Hannah J.
dc.contributor.authorAllen, Judith E
dc.contributor.authorSutherland, Tara
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2025-10-15T10:21:01Z
dc.date.issued2025-09-19
dc.descriptionWe thank S. Pearson and B. Chan at the University of Manchester and M. Robertson at the University of Aberdeen for technical support and P. Cook for advice on flow cytometry. We also thank the Flow Cytometry, Histology, and Biological Services core facilities at the University of Manchester and gratefully acknowledge the Microscopy and Histology Facility at the University of Aberdeen. For the purpose of open access, the author has applied a Creative Commons Attribution (CC BY) licence to any author-accepted manuscript version arising from this submission.en
dc.description.statusPeer revieweden
dc.format.extent29502965
dc.identifier308366304
dc.identifiera6e82401-a9ef-449c-b2d1-b3c574978264
dc.identifier40971449
dc.identifier105016673819
dc.identifier.citationParkinson, J E, Tompkins, H E, Chakraborty, A, Burgess, M, Dodd, R J, Adamson, A, MacDonald, A, Gibbs, J E, Durrington, H J, Allen, J E & Sutherland, T 2025, 'Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins', Science Immunology, vol. 10, no. 111. https://doi.org/10.1126/sciimmunol.adk6707en
dc.identifier.doi10.1126/sciimmunol.adk6707
dc.identifier.issn2470-9468
dc.identifier.otherORCID: /0000-0001-9334-8206/work/194128462
dc.identifier.otherORCID: /0000-0001-9666-6787/work/194128753
dc.identifier.urihttps://hdl.handle.net/2164/26222
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=105016673819&partnerID=8YFLogxKen
dc.language.isoeng
dc.relation.ispartofScience Immunologyen
dc.subjectSubstantive connection via an eligible employment contracten
dc.subjectAirway Remodeling/immunologyen
dc.subjectAllergens/immunologyen
dc.subjectAnimalsen
dc.subjectAsthma/immunologyen
dc.subjectChitinase-3-Like Protein 1en
dc.subjectChitinases/immunologyen
dc.subjectExtracellular Matrix/immunologyen
dc.subjectInterleukin-13/immunologyen
dc.subjectLectinsen
dc.subjectMiceen
dc.subjectMice, Inbred C57BLen
dc.subjectMice, Knockouten
dc.subjectbeta-N-Acetylhexosaminidasesen
dc.subjectR Medicine (General)en
dc.subjectImmunology and Allergyen
dc.subjectImmunologyen
dc.subjectSupplementary Dataen
dc.subjectDASen
dc.subject.lccR1en
dc.titleAllergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteinsen
dc.typeJournal articleen

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