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Bridging the Binding Sites : Dualsteric Ligands for the Cannabinoid 2 Receptor (CB2R)

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dc.contributor.authorTutov, Anna
dc.contributor.authorSteinmüller, Sophie A. M.
dc.contributor.authorRamírez, Yesid A.
dc.contributor.authorJack, Christine E.
dc.contributor.authorRodríguez-Soacha, Diego A.
dc.contributor.authorSotriffer, Christoph
dc.contributor.authorHislop, James N.
dc.contributor.authorDecker, Michael
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Neuroscienceen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2023-03-01T12:08:01Z
dc.date.available2023-03-01T12:08:01Z
dc.date.issued2023-04-13
dc.descriptionAcknowledgements This project was financially supported by the German Research Foundation (Deutsche Forschungsgemeinschaft under DFG DE1546/10-1). Gratitude is expressed to the International Doctorate Program “Receptor Dynamics” of the Elite Network of Bavaria (ENB) for financial support of A.T. and S.A.M.S. (grant No. K-BM-2013-247). Y.A.R. was granted a scholarship by the German Academic Exchange Service (Deutscher Akademischer Austauschdienst, DAAD) program “Research stays for university academics and scientists.” D.A.R.-S. was awarded a Ph.D. scholarship by the DAAD. J.N.H. was financially supported by NHS Grampian. Furthermore, the authors thank Professor Dr. Kristina Lorenz (Institute of Pharmacology and Toxicology, University of Würzburg) for enabling them to conduct in vitro experiments in her laboratory. Open access funding enabled and organized by Projekt DEAL.en
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent1445872
dc.identifier228986601
dc.identifier992b72df-e21b-497d-9931-f218cb44d017
dc.identifier85148867313
dc.identifier.citationTutov, A, Steinmüller, S A M, Ramírez, Y A, Jack, C E, Rodríguez-Soacha, D A, Sotriffer, C, Hislop, J N & Decker, M 2023, 'Bridging the Binding Sites : Dualsteric Ligands for the Cannabinoid 2 Receptor (CB2R)', Advanced Therapeutics, vol. 6, no. 4, 2200260. https://doi.org/10.1002/adtp.202200260en
dc.identifier.doi10.1002/adtp.202200260
dc.identifier.iss4en
dc.identifier.issn2366-3987
dc.identifier.otherRIS: urn:A824592849D57D1B6BCA9E20106BDE32
dc.identifier.urihttps://hdl.handle.net/2164/20204
dc.identifier.vol6en
dc.language.isoeng
dc.relation.ispartofAdvanced Therapeuticsen
dc.subjectefficacyen
dc.subjectG protein-coupled receptoren
dc.subjectheterobivalenten
dc.subjectpositive allosteric modulatoren
dc.subjectR Medicineen
dc.subjectSupplementary Informationen
dc.subject.lccRen
dc.titleBridging the Binding Sites : Dualsteric Ligands for the Cannabinoid 2 Receptor (CB2R)en
dc.typeJournal articleen

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