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EBV T-cell immunotherapy generated by peptide selection has enhanced effector functionality compared to LCL stimulation

dc.contributor.authorCooper, Rachel S.
dc.contributor.authorSutherland, Catherine
dc.contributor.authorSmith, Linda M.
dc.contributor.authorCowan, Graeme
dc.contributor.authorBarnett, Mark
dc.contributor.authorMitchell, Donna
dc.contributor.authorMcLean, Colin
dc.contributor.authorImlach, Stuart
dc.contributor.authorHayes, Alan
dc.contributor.authorZahra, Sharon
dc.contributor.authorManchanayake, Champa
dc.contributor.authorVickers, Mark
dc.contributor.authorGraham, Gerry
dc.contributor.authorMcGowan, Neil
dc.contributor.authorTurner, Marc L
dc.contributor.authorCampbell, John D M
dc.contributor.authorFraser, Alasdair R
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2025-01-06T13:05:01Z
dc.date.available2025-01-06T13:05:01Z
dc.date.issued2024-07-01
dc.descriptionThe authors gratefully acknowledge the voluntary donations of peripheral blood and leukapheresis material used in this study. This study was supported by both SNBTS Clinical Apheresis Units and the New Zealand Blood Transfusion Service for the collection of donor leukapheresis material. We also thank the whole SNBTS donor, processing, testing, medical, and nursing teams for their contributions. We would also like to expressly thank Gwen Wilkie and Kirsty Cheal for their work in developing and manufacturing the LCL-derived VST bank and Amy Muir for her contribution in initial peptide-derived VST development during her summer project.en
dc.description.statusPeer revieweden
dc.format.extent16
dc.format.extent5641716
dc.identifier300224615
dc.identifierb3d808f7-ec20-4660-8d56-ef8443e45e96
dc.identifier85198499341
dc.identifier.citationCooper, R S, Sutherland, C, Smith, L M, Cowan, G, Barnett, M, Mitchell, D, McLean, C, Imlach, S, Hayes, A, Zahra, S, Manchanayake, C, Vickers, M, Graham, G, McGowan, N, Turner, M L, Campbell, J D M & Fraser, A R 2024, 'EBV T-cell immunotherapy generated by peptide selection has enhanced effector functionality compared to LCL stimulation', Frontiers in Immunology, vol. 15. https://doi.org/10.3389/fimmu.2024.1412211en
dc.identifier.doi10.3389/fimmu.2024.1412211
dc.identifier.issn1664-3224
dc.identifier.otherORCID: /0000-0002-3154-1040/work/175114425
dc.identifier.urihttps://hdl.handle.net/2164/24827
dc.identifier.vol15en
dc.language.isoeng
dc.relation.ispartofFrontiers in Immunologyen
dc.subjectcell therapyen
dc.subjectEpstein-Barr virusen
dc.subjectimmunotherapyen
dc.subjectT cellen
dc.subjectpotencyen
dc.subjectpeptideen
dc.subjectlymphoblastoid cell lineen
dc.subjectT cell receptoren
dc.subjectR Medicine (General)en
dc.subjectSupplementary Informationen
dc.subjecthttps://www.frontiersin.org/articles/10.3389/fimmu.2024.1412211/full#supplementary-materialen
dc.subject.lccR1en
dc.titleEBV T-cell immunotherapy generated by peptide selection has enhanced effector functionality compared to LCL stimulationen
dc.typeJournal articleen

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