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A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicing

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dc.contributor.authorPandarakalam, George Cherian
dc.contributor.authorSpeake, Michael
dc.contributor.authorMcElroy, Stuart
dc.contributor.authorAlturkistani, Ammar
dc.contributor.authorPhilippe, Lucas
dc.contributor.authorPettitt, Jonathan
dc.contributor.authorMuller, Berndt
dc.contributor.authorConnolly, Bernadette
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2019-04-23T16:00:08Z
dc.date.available2019-04-23T16:00:08Z
dc.date.issued2019-08
dc.descriptionThe work was supported by the Biotechnology and Biological Sciences Research Council [Project grant BB/J007137/1] and a Medical Research Council (MRC) Confidence in Concept (2014) - University of Aberdeen Award (MC_PC_14114v.2). AA was supported by a PhD stipend from the Saudi Arabia. Research data will be made available on requesten
dc.description.statusPeer revieweden
dc.format.extent10
dc.format.extent2178964
dc.identifier142666006
dc.identifiera51f4363-83bb-4fd0-9b8b-a79c1a743a6a
dc.identifier85064465483
dc.identifier31015150
dc.identifier000485876400004
dc.identifier.citationPandarakalam, G C, Speake, M, McElroy, S, Alturkistani, A, Philippe, L, Pettitt, J, Muller, B & Connolly, B 2019, 'A high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans -splicing', International Journal for Parasitology: Drugs and Drug Resistance, vol. 10, pp. 28-37. https://doi.org/10.1016/j.ijpddr.2019.04.001, https://doi.org/10.1016/j.ijpddr.2019.04.001en
dc.identifier.doi10.1016/j.ijpddr.2019.04.001
dc.identifier.issn2211-3207
dc.identifier.otherORCID: /0000-0003-1279-5421/work/60546368
dc.identifier.otherMendeley: fb833ff4-7894-3067-9776-3113644de2e2
dc.identifier.otherORCID: /0000-0001-8195-7880/work/57461208
dc.identifier.otherORCID: /0000-0001-7988-6833/work/160389554
dc.identifier.otherORCID: /0000-0003-1279-5421/work/60546368
dc.identifier.urihttp://hdl.handle.net/2164/12209
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85064465483&partnerID=8YFLogxKen
dc.identifier.urlhttp://www.mendeley.com/research/highthroughput-screen-identification-compounds-inhibit-nematode-gene-expression-targeting-spliced-leen
dc.identifier.vol10en
dc.language.isoeng
dc.relation.ispartofInternational Journal for Parasitology: Drugs and Drug Resistanceen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectAnthelminiticsen
dc.subjectcaenorhabditis elegansen
dc.subjectSinefunginen
dc.subjectSL1 trans-splicingen
dc.subjectHTS assayen
dc.subjectCaenorhabditis elegansen
dc.subjectINFECTIONSen
dc.subject2 DISTINCTen
dc.subjectPOTENT INHIBITORen
dc.subjectMESSENGER-RNASen
dc.subjectCAENORHABDITIS-ELEGANSen
dc.subjectMETHYLTRANSFERASESen
dc.subjectSINEFUNGINen
dc.subjectSMen
dc.subjectPROTEINSen
dc.subjectR Medicine (General)en
dc.subjectInfectious Diseasesen
dc.subjectPharmacology (medical)en
dc.subjectParasitologyen
dc.subjectMedical Research Council (MRC)en
dc.subjectMC_PC_14114v.2en
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/J007137/1en
dc.subject.lccR1en
dc.titleA high-throughput screen for the identification of compounds that inhibit nematode gene expression by targeting spliced leader trans-splicingen
dc.typeJournal articleen

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