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Distinct neuroinflammatory signatures exist across genetic and sporadic ALS cohorts

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dc.contributor.authorRifai, Olivia M
dc.contributor.authorO'shaughnessy, Judi
dc.contributor.authorDando, Owen
dc.contributor.authorMunro, Alison F.
dc.contributor.authorSewell, Michael D.E.
dc.contributor.authorAbrahams, Sharon
dc.contributor.authorWaldron, Fergal
dc.contributor.authorSibley, Christopher R.
dc.contributor.authorGregory, Jenna
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Neuroscienceen
dc.date.accessioned2023-06-22T11:22:01Z
dc.date.available2023-06-22T11:22:01Z
dc.date.issued2023-01-20
dc.descriptionAcknowledgments This research was funded in part by the Wellcome Trust (108890/Z/15/Z) to OMR, a Pathological Society and Jean Shanks Foundation grant (JSPS CLSG 202002) to JMG and JOS, an NIH grant (5-R01-NS127186-02) to JMG, FMW, and JOS, a Motor Neuron Disease (MND) Scotland grant to JMG and CRS (2021/MNDS/RP/8440GREG), and a Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (215454/Z/19/Z) to CRS. For the purpose of open access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. This work would not be possible without the resources of the Edinburgh Brain Bank. The authors declare no conflicts of interest.en
dc.format.extent2429025
dc.identifier229231231
dc.identifier85df41cb-1ab2-4287-98fd-faddb5c89ee4
dc.identifier.citationRifai, O M, O'shaughnessy, J, Dando, O, Munro, A F, Sewell, M D E, Abrahams, S, Waldron, F, Sibley, C R & Gregory, J 2023 'Distinct neuroinflammatory signatures exist across genetic and sporadic ALS cohorts' bioRxiv. https://doi.org/10.1101/2023.01.19.524561en
dc.identifier.doi10.1101/2023.01.19.524561
dc.identifier.otherORCID: /0000-0003-2622-0776/work/137686262
dc.identifier.otherORCID: /0000-0003-3337-4079/work/137686565
dc.identifier.urihttps://hdl.handle.net/2164/20968
dc.language.isoeng
dc.publisherbioRxiv
dc.subject2040 Health, Nutrition and Wellbeingen
dc.subjectAmyotrophic lateral sclerosisen
dc.subjectfrontotemporal dementiaen
dc.subjectC9orf72en
dc.subjectneuroinflammationen
dc.subjectcognitive impairmenten
dc.subjectpost-mortem tissueen
dc.subjectNanoStringen
dc.subjectRC0321 Neuroscience. Biological psychiatry. Neuropsychiatryen
dc.subjectWellcome Trusten
dc.subject108890/Z/15/Zen
dc.subject.lccRC0321en
dc.titleDistinct neuroinflammatory signatures exist across genetic and sporadic ALS cohortsen
dc.typePreprinten

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