University of Aberdeen logo

AURA - Aberdeen University Research Archive

 

Chromosome-autonomous feedback down-regulates meiotic DNA break competence upon synaptonemal complex formation

Simple item page
dc.contributor.authorMu, Xiaojing
dc.contributor.authorMurakami, Hajime
dc.contributor.authorMohibullah, Neeman
dc.contributor.authorKeeny, Scott
dc.contributor.institutionUniversity of Aberdeen.Molecular and Cellular Functionen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2023-05-01T14:18:01Z
dc.date.available2023-05-01T14:18:01Z
dc.date.issued2020-11
dc.descriptionWe are grateful to Michael Lichten and Rodney Rothstein for providing strains and plasmids, Miki Shinohara and Keun Kim for discussions and sharing unpublished data, Dean Dawson and Amy MacQueen for sharing unpublished data, Agnes Viale (Memorial Sloan Kettering Cancer Center [MSKCC] Integrated Genomics Core Laboratory) for sequencing, Nicholas Socci (MSKCC Bioinformatics Core Facility) for mapping sequence reads, Stewart Shuman for gifts of T4 RNA ligase, and members of the S.K. laboratory, especially Shintaro Yamada and Devanshi Jain, for discussion and comments on the manuscript. MSKCC core facilities are supported by Cancer Center Support Grant P30 CA008748. This work was supported by National Institute of General Medical Sciences grant R35 GM118092 to S.K. Author contributions: X.M. performed experiments. X.M. analyzed Spo11-oligo map data with contributions from H.M. N.M. generated the Spo11-oligo map of the trisomy XV strain. X.M., H.M., and S.K. designed the study and wrote the paper. H.M. and S.K. supervised the research. S.K. secured fundingen
dc.description.statusPeer revieweden
dc.format.extent15
dc.format.extent2396388
dc.identifier221357745
dc.identifier360702a8-d6f6-4190-bfef-332f4fc6e558
dc.identifier85097112329
dc.identifier.citationMu, X, Murakami, H, Mohibullah, N & Keeny, S 2020, 'Chromosome-autonomous feedback down-regulates meiotic DNA break competence upon synaptonemal complex formation', Genes & Development, vol. 34, pp. 1605-1618. https://doi.org/10.1101/gad.342873.120en
dc.identifier.doi10.1101/gad.342873.120
dc.identifier.issn0890-9369
dc.identifier.otherORCID: /0000-0002-7022-6887/work/83374366
dc.identifier.urihttps://hdl.handle.net/2164/20598
dc.identifier.urlhttp://dx.doi.org/10.1101/gad.342873.120en
dc.identifier.vol34en
dc.language.isoeng
dc.relation.ispartofGenes & Developmenten
dc.subjectaneuploidyen
dc.subjectdouble-strand breaksen
dc.subjectmeiosisen
dc.subjectrecombinationen
dc.subjecttrisomyen
dc.subjectsynaptonemal complexen
dc.subjectSpo11en
dc.subjectR Medicineen
dc.subjectSupplementary Informationen
dc.subjectSupplemental material is available for this articleen
dc.subject.lccRen
dc.titleChromosome-autonomous feedback down-regulates meiotic DNA break competence upon synaptonemal complex formationen
dc.typeJournal articleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Mu_etal_Chromosome_autonomous_feedback_downregulates_VOR.pdf
Size:
2.29 MB
Format:
Adobe Portable Document Format
Download

Collections

All research

The Sir Duncan Rice Library

University of Aberdeen

Bedford Road

Aberdeen

AB24 3AA


Tel: +44 (0)1224 273330

Email: library@abdn.ac.uk

Share and keep up to date


FacebookTwitterWordpress