Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies
| dc.contributor.author | Walker, Louise A | |
| dc.contributor.author | Lee, Keunsook | |
| dc.contributor.author | Munro, Carol A | |
| dc.contributor.author | Gow, Neil A R | |
| dc.contributor.institution | University of Aberdeen.Medical Sciences | en |
| dc.date.accessioned | 2015-09-23T09:03:02Z | |
| dc.date.available | 2015-09-23T09:03:02Z | |
| dc.date.issued | 2015-10 | |
| dc.description | Date of Acceptance: 23/07/2015 We thank Gillian Milne for help with electron microscopy, Sophie M. Schäfer for pilot experiments, and Emilia Mellado for strains. All authors acknowledge financial support of Gilead Sciences through Ph.D. studentships for L.A.W. and K.K.L. We also acknowledge research grants from the Wellcome Trust (080088, 086827, 075470, 099215, and 097377) and the British Society for Antimicrobial Chemotherapy. | en |
| dc.description.status | Peer reviewed | en |
| dc.format.extent | 10 | |
| dc.format.extent | 1558532 | |
| dc.identifier | 53972144 | |
| dc.identifier | 8a0fae7e-fea4-4c01-94d9-845a7fd61da1 | |
| dc.identifier | 26169407 | |
| dc.identifier | 26169407 | |
| dc.identifier | 84942291912 | |
| dc.identifier.citation | Walker, L A, Lee, K, Munro, C A & Gow, N A R 2015, 'Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies', Antimicrobial Agents and Chemotherapy, vol. 59, no. 10, pp. 5932-5941. https://doi.org/10.1128/AAC.00862-15 | en |
| dc.identifier.doi | 10.1128/AAC.00862-15 | |
| dc.identifier.iss | 10 | en |
| dc.identifier.issn | 0066-4804 | |
| dc.identifier.other | ORCID: /0000-0002-2236-8776/work/100346473 | |
| dc.identifier.other | ORCID: /0000-0003-0761-1755/work/162729028 | |
| dc.identifier.uri | http://hdl.handle.net/2164/4935 | |
| dc.identifier.vol | 59 | en |
| dc.language.iso | eng | |
| dc.relation.ispartof | Antimicrobial Agents and Chemotherapy | en |
| dc.subject | chitin | en |
| dc.subject | drug resistance | en |
| dc.subject | echinocandin | en |
| dc.subject | fungal cell wall | en |
| dc.subject | signal transduction | en |
| dc.subject | QR Microbiology | en |
| dc.subject.lcc | QR | en |
| dc.title | Caspofungin Treatment of Aspergillus fumigatus Results in ChsG-Dependent Upregulation of Chitin Synthesis and the Formation of Chitin-Rich Microcolonies | en |
| dc.type | Journal article | en |