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A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives

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dc.contributor.authorLazzari, Paolo
dc.contributor.authorDistinto, Rita
dc.contributor.authorManca, Ilaria
dc.contributor.authorBaillie, Gemma
dc.contributor.authorMurineddu , Gabriele
dc.contributor.authorPira, Marilena
dc.contributor.authorFalzoi, Matteo
dc.contributor.authorSani, Monica
dc.contributor.authorMorales, Paula
dc.contributor.authorRoss, Ruth
dc.contributor.authorZanda, Matteo
dc.contributor.authorJagerovic , Nadine
dc.contributor.authorPinna, Gerard Aime
dc.contributor.institutionUniversity of Aberdeen.Biological Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciences - Cardiovascular Groupen
dc.date.accessioned2017-05-06T23:01:29Z
dc.date.available2017-05-06T23:01:29Z
dc.date.embargoedUntil2017-05-06
dc.date.issued2016-10-04
dc.descriptionWe thank European Commission (project “PET BRAIN: Mapping the brain with PET radiolabeled cannabinoid CB1 ligands”; FP7-People-2009-IAPP; Grant Agreement N.25142).en
dc.description.statusPeer revieweden
dc.format.extent15
dc.format.extent894741
dc.identifier66637117
dc.identifierc627ba0b-7b90-4a66-bd46-37e8827264ae
dc.identifier84971349335
dc.identifier.citationLazzari, P, Distinto, R, Manca, I, Baillie, G, Murineddu , G, Pira, M, Falzoi, M, Sani, M, Morales, P, Ross, R, Zanda, M, Jagerovic , N & Pinna, G A 2016, 'A critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivatives', European Journal of Medicinal Chemistry, vol. 121, pp. 194-208. https://doi.org/10.1016/j.ejmech.2016.05.011en
dc.identifier.doi10.1016/j.ejmech.2016.05.011
dc.identifier.issn0223-5234
dc.identifier.urihttp://hdl.handle.net/2164/8608
dc.identifier.vol121en
dc.language.isoeng
dc.relation.ispartofEuropean Journal of Medicinal Chemistryen
dc.subjectcannabinoidsen
dc.subjectendocannabinoid system (ECS)en
dc.subject8-chloro-1-(2’,4’-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamideen
dc.subjectcannabinoid receptor binding assaysen
dc.subjectCB1 receptor ligandsen
dc.subjectQH301 Biologyen
dc.subject.lccQH301en
dc.titleA critical review of both the synthesis approach and the receptor profile of the 8-chloro-1-(2′,4′-dichlorophenyl)-N-piperidin-1-yl-1,4,5,6-tetrahydrobenzo[6,7]cyclohepta[1,2-c]pyrazole-3-carboxamide and analogue derivativesen
dc.typeJournal articleen

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