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Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY) : a randomised, controlled, open-label, platform trial

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dc.contributor.authorRECOVERY Collaborative Group
dc.contributor.authorCooper, Jamie
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2024-03-15T17:18:01Z
dc.date.available2024-03-15T17:18:01Z
dc.date.issued2024-01-31
dc.descriptionFunding UK Research and Innovation (Medical Research Council) and National Institute for Health and Care Research (Grant ref: MC_PC_19056). Acknowledgements Above all, we would like to thank the patients who participated in this trial. We would also like to thank the many doctors, nurses, pharmacists, other allied health professionals, and research administrators at NHS hospital organisations across the whole of the UK, supported by staff at the National Institute of Health Research (NIHR) Clinical Research Network, NHS DigiTrials, Public Health England, Department of Health & Social Care, the Intensive Care National Audit & Research Centre, Public Health Scotland, National Records Service of Scotland, the Secure Anonymised Information Linkage (SAIL) at University of Swansea, and the NHS in England, Scotland, Wales and Northern Ireland. The RECOVERY trial is supported by grants to the University of Oxford from UK Research and Innovation (UKRI) and NIHR (MC_PC_19056), the Wellcome Trust (Grant Ref: 222406/Z/20/Z) through the COVID-19 Therapeutics Accelerator, and by core funding provided by the NIHR Oxford Biomedical Research Centre, the Wellcome Trust, the Bill and Melinda Gates Foundation, the Foreign, Commonwealth and Development Office, Health Data Research UK, the Medical Research Council Population Health Research Unit, the NIHR Health Protection Unit in Emerging and Zoonotic Infections, and NIHR Clinical Trials Unit Support Funding. TJ is supported by a grant from UK Medical Research Council (MC_UU_0002/14). WSL is supported by core funding provided by NIHR Nottingham Biomedical Research Centre. Tocilizumab was provided free of charge for this trial by Roche Products Limited. Regeneron Pharmaceuticals supported the trial through provision of casirivimab and imdevimab. The views expressed in this publication are those of the authors and not necessarily those of the NHS, the NIHR, or the UK Department of Health and Social Care. For the purpose of Open Access, the author has applied a CC BY public copyright licence to any Author Accepted Manuscript version arising from this submission. The sponsor was not involved in study design, data collection and analysis or manuscript writing.en
dc.description.statusPeer revieweden
dc.format.extent13
dc.format.extent1130826
dc.identifier284880801
dc.identifierc0775349-e24c-4a50-b36e-b420c159e780
dc.identifier85184143675
dc.identifier38296965
dc.identifier.citationRECOVERY Collaborative Group & Cooper, J 2024, 'Dimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY) : a randomised, controlled, open-label, platform trial', Nature Communications, vol. 15, no. 1, 924. https://doi.org/10.1101/2022.09.23.22280285, https://doi.org/10.1038/s41467-023-43644-xen
dc.identifier.doi10.1101/2022.09.23.22280285
dc.identifier.iss1en
dc.identifier.issn2041-1723
dc.identifier.otherunpaywall: 10.1101/2022.09.23.22280285
dc.identifier.otherORCID: /0000-0002-1397-4272/work/155729457
dc.identifier.otherPubMedCentral: PMC10831058
dc.identifier.otherORCID: /0000-0003-3812-7026/work/188766572
dc.identifier.urihttps://hdl.handle.net/2164/23034
dc.identifier.vol15en
dc.language.isoeng
dc.relation.ispartofNature Communicationsen
dc.subjectAdulten
dc.subjectHumansen
dc.subjectCOVID-19en
dc.subjectDimethyl Fumarate/therapeutic useen
dc.subjectSARS-CoV-2en
dc.subjectHospitalizationen
dc.subjectHospitalsen
dc.subjectTreatment Outcomeen
dc.subjectR Medicineen
dc.subjectMedical Research Council (MRC)en
dc.subjectMC_UU_0002/14en
dc.subjectMC_PC_19056en
dc.subjectWellcome Trusten
dc.subject222406/Z/20/Zen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleDimethyl fumarate in patients admitted to hospital with COVID-19 (RECOVERY) : a randomised, controlled, open-label, platform trialen
dc.typeJournal articleen

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