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EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor

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dc.contributor.authorMoll, Eva De
dc.contributor.authorFenwick, R. Bryn
dc.contributor.authorPhang, Christopher T.W.
dc.contributor.authorBuzon, Victor
dc.contributor.authorSzulc, Elzbieta
dc.contributor.authorDe La Fuente, Alex
dc.contributor.authorEscobedo, Albert
dc.contributor.authorGarcia, Jesus
dc.contributor.authorBertoncini, Carlos W.
dc.contributor.authorEstebanez-Perpina, Eva
dc.contributor.authorMcEwan, Iain J.
dc.contributor.authorRiera, Antoni
dc.contributor.authorSalvatella, Xavier
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2017-08-10T15:00:33Z
dc.date.available2017-08-10T15:00:33Z
dc.date.embargoedUntil2017-06-29
dc.date.issued2016-09-16
dc.descriptionACKNOWLEDGEMENTS We thank J. M. Valverde (IRB) as well as the NMR facilities of the University of Barcelona (CCiT UB) and the Instituto de Química Física Rocasolano (IQFR, CSIC) for their assistance in, respectively, protein production and NMR. This work was supported by IRB, ICREA (X.S.), Obra Social “la Caixa” (Fellowship to E.D.M. and CancerTec grants to X.S.) MICINN (CTQ2009-08850 to X.S.), MINECO (BIO2012-31043 to X.S.; CTQ2014-56361-P to A.R), Marató de TV3 (102030 to X.S. and 102031 to E.E.P) the COFUND programme of the European Commission (C.T.W.P., A. R. and X.S.), the European Research Council (CONCERT, contract number 648201, to X.S.), the Ramón y Cajal program of MICINN (RYC-2011-07873 to C.W.B.) the Serra Hunter Programme (E.E.P.) and AGAUR (SGR-2014-56RR14 to E.E.P). IRB Barcelona is the recipient of a Severo Ochoa Award of Excellence from MINECO (Government of Spain)en
dc.description.statusPeer revieweden
dc.format.extent6
dc.format.extent1094604
dc.identifier68826843
dc.identifier186e64e2-2f32-4949-9680-b3349615a24b
dc.identifier84987892499
dc.identifier.citationMoll, E D, Fenwick, R B, Phang, C T W, Buzon, V, Szulc, E, De La Fuente, A, Escobedo, A, Garcia, J, Bertoncini, C W, Estebanez-Perpina, E, McEwan, I J, Riera, A & Salvatella, X 2016, 'EPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptor', ACS Chemical Biology, vol. 11, no. 9, pp. 2499-2505. https://doi.org/10.1021/acschembio.6b00182en
dc.identifier.doi10.1021/acschembio.6b00182
dc.identifier.iss9en
dc.identifier.issn1554-8929
dc.identifier.urihttp://hdl.handle.net/2164/9112
dc.identifier.vol11en
dc.language.isoeng
dc.relation.ispartofACS Chemical Biologyen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectR Medicineen
dc.subject.lccRen
dc.titleEPI-001, A Compound Active against Castration-Resistant Prostate Cancer, Targets Transactivation Unit 5 of the Androgen Receptoren
dc.typeJournal articleen

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