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Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-β-dependent mechanisms

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dc.contributor.authorShi, Xiarong
dc.contributor.authorMihaylova, Valia T.
dc.contributor.authorKuruvilla, Leena
dc.contributor.authorChen, Fang
dc.contributor.authorViviano, Stephen
dc.contributor.authorBaldassarre, Massimiliano
dc.contributor.authorSperandio, David
dc.contributor.authorMartinez, Ruben
dc.contributor.authorYue, Peng
dc.contributor.authorBates, Jamie G.
dc.contributor.authorBreckenridge, David G.
dc.contributor.authorSchlessinger, Joseph
dc.contributor.authorTurk, Benjamin E.
dc.contributor.authorCalderwood, David A.
dc.date.accessioned2017-02-03T00:29:19Z
dc.date.available2017-02-03T00:29:19Z
dc.date.embargoedUntil2017-01-18
dc.date.issued2016-08-02
dc.descriptionACKNOWLEDGMENTS. We thank Phillip B. Murray for help with the shRNA mapping pipeline and Francesc Lopez-Giraldez for help with RNAseq mapping software.en
dc.description.statusPeer revieweden
dc.format.extent9
dc.format.extent358722
dc.format.extent2424586
dc.identifier70686757
dc.identifierc70f53fe-271b-481f-866e-a0c9dab2a2d7
dc.identifier27432991
dc.identifier84982731599
dc.identifier.citationShi, X, Mihaylova, V T, Kuruvilla, L, Chen, F, Viviano, S, Baldassarre, M, Sperandio, D, Martinez, R, Yue, P, Bates, J G, Breckenridge, D G, Schlessinger, J, Turk, B E & Calderwood, D A 2016, 'Loss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-β-dependent mechanisms', PNAS, vol. 113, no. 31, pp. E4558-4566. https://doi.org/10.1073/pnas.1608319113, https://doi.org/10.1073/pnas.1608319113/-/DCSupplementalen
dc.identifier.doi10.1073/pnas.1608319113
dc.identifier.iss31en
dc.identifier.issn0027-8424
dc.identifier.otherORCID: /0000-0002-2498-4767/work/76976107
dc.identifier.urihttp://hdl.handle.net/2164/8138
dc.identifier.vol113en
dc.language.isoeng
dc.relation.ispartofPNASen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectbromodomain inhibitoren
dc.subjectTRIM33en
dc.subjectJQ1en
dc.subjectdrug resistanceen
dc.subjectTGF-βen
dc.subjectR Medicineen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleLoss of TRIM33 causes resistance to BET bromodomain inhibitors through MYC- and TGF-β-dependent mechanismsen
dc.typeJournal articleen

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