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PHF-Core Tau as the Potential Initiating Event for Tau Pathology in Alzheimer’s Disease

dc.contributor.authorLuna-Viramontes, Nabil Itzi
dc.contributor.authorCampa-Córdoba, B. Berenice
dc.contributor.authorOntiveros-Torres, Miguel Angel
dc.contributor.authorHarrington, Charles R
dc.contributor.authorVillanueva-Fierro, Ignacio
dc.contributor.authorGuadarrama-Ortíz, Parménides
dc.contributor.authorGarcés-Ramírez, Linda
dc.contributor.authorde la Cruz, Fidel
dc.contributor.authorHernandes-Alejandro, Mario
dc.contributor.authorMartínez-Robles, Sandra
dc.contributor.authorGonzález-Ballesteros, Erik
dc.contributor.authorPacheco-Herrero, Mar
dc.contributor.authorLuna-Muñoz, José
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2020-10-23T09:02:01Z
dc.date.available2020-10-23T09:02:01Z
dc.date.issued2020-09-10
dc.descriptionFUNDING This work was supported by Fondo Nacional de Ciencia, Tecnologia, FONDOCyT, from the Ministry of Higher Education, Science and Technology, Dominican Republic (2015- 3A2-127 to MP-H and 2018-2019-2A3-208 to JL-M and MP-H). ACKNOWLEDGMENTS: We want to express our gratitude to the following: Dr. P. Davies (Albert Einstein College of Medicine, Bronx, NY, United States) and Lester I. Binder† (North Western, Chicago, IL, United States) for the generous gifts of mAbs TG3 and Alz-50, and Tau-1, Tau-5, and Tau-7, respectively; Tec. Amparo Viramontes Pintos for the handling of the brain tissue; Samadhi Moreno-Campuzano for her technical assistance/support in the confocal microscopy unit of CIIDIR Durango, Instituto Politécnico Nacional; Union Medical University Clinic, Dominican Republic, for their support and collaboration in the development of this research project. We also want to express our gratitude to the Mexican families who have donated the brain of their loved ones affected with Alzheimer’s disease and made our research possible. This work is dedicated to the memory of Professor Dr. José Raúl Mena López† .en
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent3223640
dc.identifier178304792
dc.identifieraeee75f6-60fa-43af-9881-b1709a28c2ae
dc.identifier85091531587
dc.identifier33132840
dc.identifier.citationLuna-Viramontes, N I, Campa-Córdoba, B B, Ontiveros-Torres, M A, Harrington, C R, Villanueva-Fierro, I, Guadarrama-Ortíz, P, Garcés-Ramírez, L, de la Cruz, F, Hernandes-Alejandro, M, Martínez-Robles, S, González-Ballesteros, E, Pacheco-Herrero, M & Luna-Muñoz, J 2020, 'PHF-Core Tau as the Potential Initiating Event for Tau Pathology in Alzheimer’s Disease', Frontiers in cellular neuroscience, vol. 14, 247. https://doi.org/10.3389/fncel.2020.00247en
dc.identifier.doi10.3389/fncel.2020.00247
dc.identifier.issn1662-5102
dc.identifier.otherORCID: /0000-0003-2250-3920/work/173415888
dc.identifier.urihttps://hdl.handle.net/2164/15277
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85091531587&partnerID=8YFLogxKen
dc.identifier.vol14en
dc.language.isoeng
dc.relation.ispartofFrontiers in cellular neuroscienceen
dc.subjecttau proteinen
dc.subjecttau pathologyen
dc.subjectPHF coreen
dc.subjectTruncationen
dc.subjectphosphorylationen
dc.subjectconformational changesen
dc.subjectpaired helical filamenten
dc.subjectneurofibrillary tanglesen
dc.subjecttruncationen
dc.subjectR Medicineen
dc.subjectCellular and Molecular Neuroscienceen
dc.subject.lccRen
dc.titlePHF-Core Tau as the Potential Initiating Event for Tau Pathology in Alzheimer’s Diseaseen
dc.typeJournal articleen

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