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Prebiotic fructans have greater impact on luminal microbiology and CD3+ T cells in healthy siblings than patients with Crohn’s disease : a pilot study investigating the potential for primary prevention of inflammatory bowel disease

dc.contributor.authorHedin, Charlotte R
dc.contributor.authorMcCarthy, Neil E
dc.contributor.authorLouis, Petra
dc.contributor.authorFarquharson, Freda
dc.contributor.authorMcCartney, Sara
dc.contributor.authorStagg, Andrew J
dc.contributor.authorLindsay, James O
dc.contributor.authorWhelan, Kevin
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.date.accessioned2022-06-22T23:12:23Z
dc.date.available2022-06-22T23:12:23Z
dc.date.embargoedUntil2022-06-23
dc.date.issued2021-08
dc.descriptionFunding This work was supported by a clinical research fellowship granted by the charity Core (Guts UK) (CRH). FMF and PL received financial support from the Scottish Government Rural and Environment Science and Analytical Services. Acknowledgments The authors would like to acknowledge BENEO-Orafti, Teinen, Belgium who provided the oligofructose-enriched inulin. The authors would like to thank the patients and the siblings who generously participated in this study.en
dc.description.statusPeer revieweden
dc.format.extent11
dc.format.extent504529
dc.identifier194371299
dc.identifier3bbb1ee2-2d85-491e-80f3-c7ad9a154dec
dc.identifier85111883698
dc.identifier34364241
dc.identifier85111883698
dc.identifier.citationHedin, C R, McCarthy, N E, Louis, P, Farquharson, F, McCartney, S, Stagg, A J, Lindsay, J O & Whelan, K 2021, 'Prebiotic fructans have greater impact on luminal microbiology and CD3+ T cells in healthy siblings than patients with Crohn’s disease : a pilot study investigating the potential for primary prevention of inflammatory bowel disease', Clinical Nutrition, vol. 40, no. 8, pp. 5009-5019. https://doi.org/10.1016/j.clnu.2021.05.033en
dc.identifier.doi10.1016/j.clnu.2021.05.033
dc.identifier.iss8en
dc.identifier.issn0261-5614
dc.identifier.otherORCID: /0000-0003-2115-2399/work/101749490
dc.identifier.urihttps://hdl.handle.net/2164/18739
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85111883698&partnerID=8YFLogxKen
dc.identifier.vol40en
dc.language.isoeng
dc.relation.ispartofClinical Nutritionen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectPrebioticsen
dc.subjectCrohn’s diseaseen
dc.subjectmicrobiotaen
dc.subjectPre-diseaseen
dc.subjectfirst-degree relativeen
dc.subjectpreventionen
dc.subjectR Medicineen
dc.subjectRA0421 Public health. Hygiene. Preventive Medicineen
dc.subjectNutrition and Dieteticsen
dc.subjectCritical Care and Intensive Care Medicineen
dc.subjectRural and Environmental Science and Analytical Services (RESAS)en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.subject.lccRA0421en
dc.titlePrebiotic fructans have greater impact on luminal microbiology and CD3+ T cells in healthy siblings than patients with Crohn’s disease : a pilot study investigating the potential for primary prevention of inflammatory bowel diseaseen
dc.typeJournal articleen

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