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Pathway-based integration of multi-omics data reveals lipidomics alterations validated in an Alzheimer´s Disease mouse model and risk loci carriers

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dc.contributor.authorGarcia-Segura, Monica Emili
dc.contributor.authorDurainayagam, Brenan R
dc.contributor.authorLiggi, Sonia
dc.contributor.authorGraça, Gonçalo
dc.contributor.authorJimenez, Beatriz
dc.contributor.authorDehghan, Abbas
dc.contributor.authorTzoulaki, Ioanna
dc.contributor.authorKaraman, Ibrahim
dc.contributor.authorElliott, Paul
dc.contributor.authorGriffin, Jules
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.date.accessioned2023-04-06T15:06:01Z
dc.date.available2023-04-06T15:06:01Z
dc.date.issued2022-12-26
dc.descriptionAcknowledgements The authors would like to acknowledge Dr. Tomonori Aikawa and Professor Takahisa Kanekiyo from the Mayo Clinic, Jacksonville, Florida for providing the ABCA7 cortical mouse tissue. Funding Information Alzheimer's Research UK, Grant/Award Number: Imperial College Dementia Research Institute; Alzheimer's Society; Medical Research Councilen
dc.description.statusPeer revieweden
dc.format.extent20
dc.format.extent7982657
dc.identifier221853781
dc.identifierf8aae5e1-292b-4ba0-be91-ef1a55cf1c85
dc.identifier36326588
dc.identifier85144057624
dc.identifier.citationGarcia-Segura, M E, Durainayagam, B R, Liggi, S, Graça, G, Jimenez, B, Dehghan, A, Tzoulaki, I, Karaman, I, Elliott, P & Griffin, J 2022, 'Pathway-based integration of multi-omics data reveals lipidomics alterations validated in an Alzheimer´s Disease mouse model and risk loci carriers', Journal of Neurochemistry, vol. 164, no. 1, pp. 57-76. https://doi.org/10.1111/jnc.15719en
dc.identifier.doi10.1111/jnc.15719
dc.identifier.iss1en
dc.identifier.issn0022-3042
dc.identifier.otherORCID: /0000-0003-1336-7744/work/132961672
dc.identifier.urihttps://hdl.handle.net/2164/20440
dc.identifier.vol164en
dc.language.isoeng
dc.relation.ispartofJournal of Neurochemistryen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectAlzheimer's diseaseen
dc.subjectATP-binding-cassette subfamily-a member-7 gene (ABCA7)en
dc.subjectlipidomicsen
dc.subjectmetabolome-wide association study (MWAS)en
dc.subjectmulti-omicsen
dc.subjectpathway-based integrationen
dc.subjectRC0321 Neuroscience. Biological psychiatry. Neuropsychiatryen
dc.subjectQP Physiologyen
dc.subjectCellular and Molecular Neuroscienceen
dc.subjectGeneral Biochemistry,Genetics and Molecular Biologyen
dc.subjectAlzheimers Research UKen
dc.subjectMedical Research Council (MRC)en
dc.subjectSupplementary Dataen
dc.subject.lccRC0321en
dc.subject.lccQPen
dc.titlePathway-based integration of multi-omics data reveals lipidomics alterations validated in an Alzheimer´s Disease mouse model and risk loci carriersen
dc.typeJournal articleen

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