University of Aberdeen logo

AURA - Aberdeen University Research Archive

 

Replication timing maintains the global epigenetic state in human cells

dc.contributor.authorKlein, Kyle N.
dc.contributor.authorZhao, Peiyao A.
dc.contributor.authorLyu, Xiaowen
dc.contributor.authorSasaki, Takayo
dc.contributor.authorBartlett, Daniel A.
dc.contributor.authorSingh, Amar M.
dc.contributor.authorTasan, Ipek
dc.contributor.authorZhang, Meng
dc.contributor.authorWatts, Lotte P.
dc.contributor.authorHiraga, Shin-ichiro
dc.contributor.authorNatsume, Toyoaki
dc.contributor.authorZhou, Xuemeng
dc.contributor.authorBaslan, Timour
dc.contributor.authorLeung, Danny
dc.contributor.authorKanemaki, Masato T.
dc.contributor.authorDonaldson, Anne D.
dc.contributor.authorZhao, Huimin
dc.contributor.authorDalton, Stephen
dc.contributor.authorCorces, Victor G.
dc.contributor.authorGilbert, David M.
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.contributor.institutionUniversity of Aberdeen.Molecular and Cellular Functionen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2021-04-26T09:02:01Z
dc.date.available2021-04-26T09:02:01Z
dc.date.issued2021-04-23
dc.descriptionACKNOWLEDGMENTS We thank R. Didier and B. Alexander of the FSU Flow Cytometry and Confocal Microscopy Facilities for their help with flow cytometry and fluorescence-activated cell sorting for this project. Thanks to A. Brown of the FSU Biological Science Core Labs and to Y. Yang and C. Vied of the FSU Translational Labs. Thanks to S. R. Westermann of SCIGRAPHIX for generating the model figure. Thanks to B. van Steensel, J. Phillips-Cremins, and P. Fraser for critical reading of the manuscript. Funding: This work was supported by NIH grant GM083337 to D.M.G., GM035463 to V.G.C., and GM085354 to D.M.G., S.D., and V.G.C. D.L. is supported by the Hong Kong Research Grant Council (ECS 26104216). T.B. is supported by the William C. and Joyce C. O’Neil Charitable Trust, Memorial Sloan Kettering Single Cell Sequencing Initiativeen
dc.description.statusPeer revieweden
dc.format.extent8
dc.format.extent5919724
dc.identifier192052326
dc.identifier1bc1dcc8-f964-4809-8055-40d6ad51ff49
dc.identifier33888635
dc.identifier000645009800036
dc.identifier85105049527
dc.identifier.citationKlein, K N, Zhao, P A, Lyu, X, Sasaki, T, Bartlett, D A, Singh, A M, Tasan, I, Zhang, M, Watts, L P, Hiraga, S, Natsume, T, Zhou, X, Baslan, T, Leung, D, Kanemaki, M T, Donaldson, A D, Zhao, H, Dalton, S, Corces, V G & Gilbert, D M 2021, 'Replication timing maintains the global epigenetic state in human cells', Science, vol. 372, no. 6540, pp. 371-378. https://doi.org/10.1126/science.aba5545en
dc.identifier.doi10.1126/science.aba5545
dc.identifier.issn0036-8075
dc.identifier.otherBibtex: Klein371
dc.identifier.otherORCID: /0000-0002-8722-3869/work/93483360
dc.identifier.urihttps://hdl.handle.net/2164/16316
dc.language.isoeng
dc.relation.ispartofScienceen
dc.subjectSubstantive connection via an eligible employment contracten
dc.subjectR Medicineen
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleReplication timing maintains the global epigenetic state in human cellsen
dc.typeJournal articleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Kyle_etal_SCI_Replication_Timing_Maintains_AAM.pdf
Size:
5.65 MB
Format:
Adobe Portable Document Format

Collections