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Crosstalk between the calcineurin and cell wall integrity pathways prevents chitin overexpression in Candida albicans

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dc.contributor.authorda Silva Dantas, Alessandra
dc.contributor.authorNogueira, Filomena
dc.contributor.authorLee, Keunsook K.
dc.contributor.authorWalker, Louise A.
dc.contributor.authorEdmondson, Matt
dc.contributor.authorBrand, Alexandra C.
dc.contributor.authorLenardon, Megan D.
dc.contributor.authorGow, Neil A.R.
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Medicine, Medical Sciences & Nutritionen
dc.date.accessioned2022-02-17T15:22:01Z
dc.date.available2022-02-17T15:22:01Z
dc.date.issued2021-12-01
dc.descriptionFunding Information: We thank Carol Munro for helpful discussions during the research, Raif Yuecel, Elizabeth Adams, Linda Duncan, Barry Lewis and Kimberley Sim for assistance with FACS at Aberdeen Cytometry Core Facility, and Yang Meng and Dominique Sanglard with help in construction of mutants. We also thank Linghuo Jiang, David Soll, Jes?s Pla, Jan Quinn, Terry Roemer and Joseph Heitman for mutant strains. N.A.R.G. acknowledges support from the Wellcome Trust [Senior Investigator (101873/Z/13/Z), Collaborative (200208/A/15/Z and 215599/Z/19/Z) and Strategic (097377/Z11/Z) Awards] and from the Medical Research Council Centre for Medical Mycology (MR/N006364/2). This work was also supported by a Marie Curie FP7-PEOPLE-ITN-2008 grant (MB004 RGE0655 ARIADNE) and by a Wellcome Trust project grant (086827). Open access funding provided by University of Exeter. Deposited in PMC for immediate release.en
dc.description.statusPeer revieweden
dc.format.extent14
dc.format.extent8202585
dc.identifier213503538
dc.identifier869b3e94-ecdb-4982-943c-38071baa7414
dc.identifier85122772168
dc.identifier34792152
dc.identifier.citationda Silva Dantas, A, Nogueira, F, Lee, K K, Walker, L A, Edmondson, M, Brand, A C, Lenardon, M D & Gow, N A R 2021, 'Crosstalk between the calcineurin and cell wall integrity pathways prevents chitin overexpression in Candida albicans', Journal of Cell Science, vol. 134, no. 24, jcs258889. https://doi.org/10.1242/jcs.258889en
dc.identifier.doi10.1242/jcs.258889
dc.identifier.iss24en
dc.identifier.issn0021-9533
dc.identifier.urihttps://hdl.handle.net/2164/18088
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85122772168&partnerID=8YFLogxKen
dc.identifier.vol134en
dc.language.isoeng
dc.relation.ispartofJournal of Cell Scienceen
dc.subjectAntifungal drugen
dc.subjectCa-calcineurinen
dc.subjectCaspofunginen
dc.subjectCell wall stressen
dc.subjectChitinen
dc.subjectEchinocandinsen
dc.subjectR Medicine (General)en
dc.subjectQH426 Geneticsen
dc.subjectCell Biologyen
dc.subjectWellcome Trusten
dc.subject101873/Z/13/Zen
dc.subject200208/A/15/Zen
dc.subject215599/Z/19/Zen
dc.subject097377/Z11/Zen
dc.subject086827en
dc.subjectMedical Research Council (MRC)en
dc.subjectMR/N006364/2en
dc.subjectEuropean Commissionen
dc.subjectFP7-PEOPLE-ITN-2008en
dc.subjectSupplementary Informationen
dc.subject.lccR1en
dc.subject.lccQH426en
dc.titleCrosstalk between the calcineurin and cell wall integrity pathways prevents chitin overexpression in Candida albicansen
dc.typeJournal articleen

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