University of Aberdeen logo

AURA - Aberdeen University Research Archive

 

Disease associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue specific activity of the cannabinoid‐1 receptor gene promoter; implications for cannabinoid pharmacogenetics

Simple item page
dc.contributor.authorHay, Elizabeth A
dc.contributor.authorCowie, Philip
dc.contributor.authorMcEwan, Andrew R
dc.contributor.authorRoss, Ruth
dc.contributor.authorPertwee, Roger G
dc.contributor.authorMacKenzie, Alasdair
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2020-01-09T15:35:01Z
dc.date.available2020-01-09T15:35:01Z
dc.date.issued2020-01-01
dc.descriptionEH was funded by Medical Research Scotland (PhD-719-2013) and GW Pharmaceuticals. AMcE was funded by BBSRC project grant (BB/N017544/1). PB and DW are funded by the Scottish Government Rural and Environment Science and Analytical Services Division to the Rowett Institute. The authors declare no conflicts of interest.en
dc.description.statusPeer revieweden
dc.format.extent8
dc.format.extent1304614
dc.identifier147947182
dc.identifierc0735b01-0948-428b-91b8-c9411640f7d9
dc.identifier31608546
dc.identifier000493859500001
dc.identifier31608546
dc.identifier85074761900
dc.identifier.citationHay, E A, Cowie, P, McEwan, A R, Ross, R, Pertwee, R G & MacKenzie, A 2020, 'Disease associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue specific activity of the cannabinoid‐1 receptor gene promoter; implications for cannabinoid pharmacogenetics ', Human Mutation, vol. 41, no. 1, pp. 291-298. https://doi.org/10.1002/humu.23931en
dc.identifier.doi10.1002/humu.23931
dc.identifier.iss1en
dc.identifier.issn1059-7794
dc.identifier.urihttps://hdl.handle.net/2164/13486
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85074761900&partnerID=8YFLogxKen
dc.identifier.vol41en
dc.language.isoeng
dc.relation.ispartofHuman Mutationen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectDisease associated polymorphismsen
dc.subjectCannabinoid-1 receptoren
dc.subjectgene regulationen
dc.subjecttissue specificen
dc.subjectpromoteren
dc.subjectenhanceren
dc.subjectCB1 agonistsen
dc.subjecttranscription factoren
dc.subjectChromatin immunoprecipitationen
dc.subjectCannabinoid pharmacogeneticsen
dc.subjectSYSTEMen
dc.subjectcannabinoid pharmacogeneticsen
dc.subjectWin55en
dc.subjectCTCFen
dc.subjectFOSen
dc.subjectAP-1en
dc.subject212-2en
dc.subjectchromatin immunoprecipitationen
dc.subjectdisease-associated polymorphisms cannabinoid-1 receptoren
dc.subjectTRANSCRIPTIONAL REGULATIONen
dc.subjectQH426 Geneticsen
dc.subjectGenetics(clinical)en
dc.subjectGeneticsen
dc.subjectOtheren
dc.subjectPhD-719-2013en
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/N017544/1en
dc.subjectRural and Environmental Science and Analytical Services (RESAS)en
dc.subject.lccQH426en
dc.titleDisease associated polymorphisms within the conserved ECR1 enhancer differentially regulate the tissue specific activity of the cannabinoid‐1 receptor gene promoter; implications for cannabinoid pharmacogeneticsen
dc.typeJournal articleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Hay_etal_HumanMut_Disease_Associated_VOR.pdf
Size:
1.24 MB
Format:
Adobe Portable Document Format
Download

Collections

All research