University of Aberdeen logo

AURA - Aberdeen University Research Archive

 

Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain

Simple item page
dc.contributor.authorCoelho Dos Santos, Renato
dc.contributor.authorLee, Sophie H
dc.contributor.authorLofthouse, Richard Andrew
dc.contributor.authorMelis, Valeria
dc.contributor.authorStrachan, Lianne
dc.contributor.authorLeith, Michael
dc.contributor.authorDreesen, Eline
dc.contributor.authorArmstrong, Paul
dc.contributor.authorVorley, Thomas
dc.contributor.authorGoatman, Elizabeth
dc.contributor.authorHull, Claire
dc.contributor.authorRiedel, Gernot
dc.contributor.authorWischik, Claude
dc.contributor.authorHarrington, Charles
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Chemistryen
dc.contributor.institutionUniversity of Aberdeen.Neuroscienceen
dc.contributor.institutionUniversity of Aberdeen.Institute of Medical Sciencesen
dc.date.accessioned2025-04-04T15:04:01Z
dc.date.available2025-04-04T15:04:01Z
dc.date.issued2025-05
dc.descriptionOpen access via Wiley agreement The authors acknowledge Dr David Stead, Head of the Proteomics Facility, Dr Craig Pattinson and Dr Kate Burgoyne at the Rowett Institute, University of Aberdeen, for their excellent support with the processing of the proteomics samples and analyses of the data. We also acknowledge Dr Soumya Palliyil, Head of the Scottish Biologics Facility, University of Aberdeen, for providing CB7, S1D12 and S1G2 tau antibodies.en
dc.description.statusPeer revieweden
dc.format.extent22
dc.format.extent3436892
dc.identifier301115499
dc.identifier5850d85c-0ca5-4ce2-a7d3-f274c37affcf
dc.identifier39960781
dc.identifier85219730437
dc.identifier85219730437
dc.identifier.citationCoelho Dos Santos, R, Lee, S H, Lofthouse, R A, Melis, V, Strachan, L, Leith, M, Dreesen, E, Armstrong, P, Vorley, T, Goatman, E, Hull, C, Riedel, G, Wischik, C & Harrington, C 2025, 'Hydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brain', FEBS Journal, vol. 292, no. 10, pp. 2602-2623. https://doi.org/10.1111/febs.70021en
dc.identifier.doi10.1111/febs.70021
dc.identifier.iss10en
dc.identifier.issn1742-464X
dc.identifier.otherORCID: /0000-0003-3737-8296/work/181758851
dc.identifier.otherORCID: /0000-0003-2250-3920/work/181759447
dc.identifier.urihttps://hdl.handle.net/2164/25257
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85219730437&partnerID=8YFLogxKen
dc.identifier.vol292en
dc.language.isoeng
dc.relation.ispartofFEBS Journalen
dc.subjectSubstantive connection via eligible employment contracten
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjectAlzheimer's diseaseen
dc.subjectfrontotemporal dementiaen
dc.subjecthydromethylthionineen
dc.subjectneuroinflammationen
dc.subjectTau proteinen
dc.subjectMicroglia/drug effectsen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMice, Transgenicen
dc.subjectTumor Necrosis Factor-alpha/geneticsen
dc.subjectBrain/drug effectsen
dc.subjecttau Proteins/geneticsen
dc.subjectAnimalsen
dc.subjectFrontotemporal Dementia/drug therapyen
dc.subjectInflammation/drug therapyen
dc.subjectMemantine/pharmacologyen
dc.subjectMiceen
dc.subjectTauopathies/drug therapyen
dc.subjectDisease Models, Animalen
dc.subjectRC0321 Neuroscience. Biological psychiatry. Neuropsychiatryen
dc.subjectBiochemistryen
dc.subjectMolecular Biologyen
dc.subjectCell Biologyen
dc.subjectSupplementary Dataen
dc.subjectDASen
dc.subjectLinken
dc.subject.lccRC0321en
dc.titleHydromethylthionine sustains truncated tau-dependent inflammation-lowering effects in mouse brainen
dc.typeJournal articleen

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
Santos_etal_FEBS_Hydromethylthionine_Sustains_Truncated_VoR.pdf
Size:
3.28 MB
Format:
Adobe Portable Document Format
Download

Collections

All research