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Genome sequencing and transcriptome analyses of the Siberian hamster hypothalamus identify mechanisms for seasonal energy balance

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dc.contributor.authorBao, Riyue
dc.contributor.authorOnishi, Kenneth G.
dc.contributor.authorTolla, Elisabetta
dc.contributor.authorEbling, Fran J. P.
dc.contributor.authorLewis, Jo E
dc.contributor.authorAnderson, Richard L.
dc.contributor.authorBarrett, Perry
dc.contributor.authorPrendergast, Brian J.
dc.contributor.authorStevenson, Tyler J.
dc.contributor.institutionUniversity of Aberdeen.Biological Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Rowett Instituteen
dc.date.accessioned2019-07-02T13:20:05Z
dc.date.available2019-07-02T13:20:05Z
dc.date.issued2019-06-25
dc.descriptionWe thank the manuscript reviewers for constructive feedback; David G. Hazlerigg, Cristina Saenz de Miera, and Valerie Simonneaux for genome sequence contributions; Nicolas Scrutton and Lindsey Duguid for expert technical assistance; and Michael Jarsulic for technical assistance on the high-performance computing clusters. This project was supported by a project research grant from The British Society for Neuroendocrinology (to T.J.S.); Grants BB/M021629/1 and BB/M001555/1 (to F.J.P.E.) from the Biotechnology and Biological Sciences Research Council, and Grants UL1-TR000430 (to T.J.S. and B.J.P.) and R01-AI067406 (to B.J.P.) from the National Institutes of Health. T.J.S. is funded by The Leverhulme Trust. The Center for Research Informatics was supported by the Biological Sciences Division at the University of Chicago with additional support provided by the Institute for Translational Medicine/Clinical and Translational award (NIH 5UL1TR002389-02) and the University of Chicago Comprehensive Cancer Center Support Grant (NIH Grant P30CA014599). The bioinformatics analysis was performed on high-performance computing clusters at the Center for Research Informatics, Biological Sciences Division. P.B. was funded by the Scottish Government Rural and Environment Science and Analytical Services Division grant to the Rowett Institute.en
dc.description.statusPeer revieweden
dc.format.extent6
dc.format.extent930892
dc.identifier144155512
dc.identifier1454b627-0adb-483b-a80b-45e57b2bfe95
dc.identifier31189592
dc.identifier85068148767
dc.identifier000472719100084
dc.identifier.citationBao, R, Onishi, K G, Tolla, E, Ebling, F J P, Lewis, J E, Anderson, R L, Barrett, P, Prendergast, B J & Stevenson, T J 2019, 'Genome sequencing and transcriptome analyses of the Siberian hamster hypothalamus identify mechanisms for seasonal energy balance', PNAS, vol. 116, no. 26, pp. 13116-13121. https://doi.org/10.1073/pnas.1902896116en
dc.identifier.doi10.1073/pnas.1902896116
dc.identifier.iss26en
dc.identifier.issn0027-8424
dc.identifier.otherMendeley: 3313059f-48a0-3731-8def-2b70ce338059
dc.identifier.otherORCID: /0000-0003-3604-2950/work/76975672
dc.identifier.urihttp://hdl.handle.net/2164/12482
dc.identifier.urlhttp://www.mendeley.com/research/genome-sequencing-transcriptome-analyses-siberian-hamster-hypothalamus-identify-mechanisms-seasonalen
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85068148767&partnerID=8YFLogxKen
dc.identifier.urlhttp://www.pnas.org/lookup/suppl/doi:10.1073/pnas.1902896116/-/DCSupplementalen
dc.identifier.urlhttps://www.ncbi.nlm.nih.gov/nuccore/1056038647en
dc.identifier.vol116en
dc.language.isoeng
dc.relation.ispartofPNASen
dc.subjectSDG 3 - Good Health and Well-beingen
dc.subjecttriiodothyronineen
dc.subjectproopiomelanocortinen
dc.subjectseasonalen
dc.subjectobesityen
dc.subjectObesityen
dc.subjectProopiomelanocortinen
dc.subjectTriiodothyronineen
dc.subjectSeasonalen
dc.subjectFOOD-INTAKEen
dc.subjectINFORMATIONen
dc.subjectRECEPTORen
dc.subjectIODOTHYRONINE DEIODINASE EXPRESSIONen
dc.subjectPHOTOPERIODen
dc.subjectBODY-WEIGHTen
dc.subjectPROOPIOMELANOCORTINen
dc.subjectGENE-EXPRESSIONen
dc.subjectMICEen
dc.subjectREPRODUCTIONen
dc.subjectQH426 Geneticsen
dc.subjectGeneralen
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectBB/M021629/1en
dc.subjectBB/M001555/1en
dc.subjectOtheren
dc.subjectUL1-TR000430en
dc.subjectR01-AI067406en
dc.subject5UL1TR002389-02en
dc.subjectP30CA014599en
dc.subjectSupplementary Dataen
dc.subject.lccQH426en
dc.titleGenome sequencing and transcriptome analyses of the Siberian hamster hypothalamus identify mechanisms for seasonal energy balanceen
dc.typeJournal articleen

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