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Activin type I receptor polymorphisms and body composition in older individuals with sarcopenia – analyses from the LACE randomised controlled trial

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dc.contributor.authorBashir, Tufail
dc.contributor.authorAchison, Marcus
dc.contributor.authorAdamson, Simon
dc.contributor.authorAkpan, Asangaedem
dc.contributor.authorAspray, Terry J.
dc.contributor.authorAvenell, Alison
dc.contributor.authorBurton, Louise A
dc.contributor.authorCvoro, Vera
dc.contributor.authorDonnan, Peter T.
dc.contributor.authorDuncan, Gordon W
dc.contributor.authorGeorge, Jacob
dc.contributor.authorGordon, Adam L
dc.contributor.authorGregson, Celia L
dc.contributor.authorHapca, Adrian
dc.contributor.authorHume, Cheryl L
dc.contributor.authorJackson, Thomas
dc.contributor.authorKerr, Simon
dc.contributor.authorKilgour, Alixe H. M.
dc.contributor.authorMasud, Tahir
dc.contributor.authorMcKenzie, Andrew
dc.contributor.authorMcKenzie, Emma
dc.contributor.authorPatel, Harnish
dc.contributor.authorPilvinyte, Kristina
dc.contributor.authorRoberts, Helen C.
dc.contributor.authorRossios, Christos
dc.contributor.authorSayer, Avan Aihie
dc.contributor.authorSmith, Karen T
dc.contributor.authorSoiza, Roy
dc.contributor.authorSteves, Claire J.
dc.contributor.authorStruthers, Allan D
dc.contributor.authorTiwari, Divya
dc.contributor.authorWhitney, Julie
dc.contributor.authorWitham, Miles D
dc.contributor.authorKemp, Paul R
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Centre for Evaluationen
dc.contributor.institutionUniversity of Aberdeen.Institute of Applied Health Sciencesen
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.date.accessioned2024-02-06T17:02:01Z
dc.date.available2024-02-06T17:02:01Z
dc.date.issued2023-11-14
dc.descriptionAcknowledgements AAS, TA, and MDW acknowledge support from the NIHR Newcastle Biomedical Research Centre. AA acknowledges support from the Health Services Research Unit, which is core funded by the Chief Scientist Office of the Scottish Government Health and Social Care Directorate. The authors acknowledge support from the NIHR Ageing Clinical Research Network and the NHS Scotland Support for Science programme. The authors would also thank the efforts of all the research nurses and other site research staff who recruited participants to the trial, all the participants, and all the staff of the Tayside Clinical Trials Unit for their support of the trial. Funding Information: The LACE trial (project reference 13/53/ 03) was funded by the Efficacy and Mechanism Evaluation (EME) Programme, an MRC and NIHR partnership (https://www.nihr.ac.uk/explore-nihr/ funding-programmes/efficacy-and-mechanismevaluation.htm). The Principal Investigator of the award was MW with PK, AS, AA, PD as co applicants. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. The views expressed in this publication are those of the authors and not necessarily those of the MRC, NIHR or the Department of Health and Social Care. Publisher Copyright: Copyright: © 2023 Bashir et al.en
dc.description.statusPeer revieweden
dc.format.extent18
dc.format.extent1303200
dc.identifier282159436
dc.identifiereda60d54-c7d1-44e9-b75a-2cecc1f969c9
dc.identifier85176735112
dc.identifier37963137
dc.identifier.citationBashir, T, Achison, M, Adamson, S, Akpan, A, Aspray, T J, Avenell, A, Burton, L A, Cvoro, V, Donnan, P T, Duncan, G W, George, J, Gordon, A L, Gregson, C L, Hapca, A, Hume, C L, Jackson, T, Kerr, S, Kilgour, A H M, Masud, T, McKenzie, A, McKenzie, E, Patel, H, Pilvinyte, K, Roberts, H C, Rossios, C, Sayer, A A, Smith, K T, Soiza, R, Steves, C J, Struthers, A D, Tiwari, D, Whitney, J, Witham, M D & Kemp, P R 2023, 'Activin type I receptor polymorphisms and body composition in older individuals with sarcopenia – analyses from the LACE randomised controlled trial', PloS ONE, vol. 18, no. 11 November, e0294330. https://doi.org/10.1371/journal.pone.0294330en
dc.identifier.doi10.1371/journal.pone.0294330
dc.identifier.iss11en
dc.identifier.issn1932-6203
dc.identifier.otherORCID: /0000-0002-1397-4272/work/148505596
dc.identifier.otherORCID: /0000-0003-4813-5628/work/167120257
dc.identifier.urihttps://hdl.handle.net/2164/22721
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85176735112&partnerID=8YFLogxKen
dc.identifier.vol18en
dc.language.isoeng
dc.relation.ispartofPloS ONEen
dc.subjectSarcopeniaen
dc.subjectActivin receptoren
dc.subjectpolymorphismen
dc.subjectbody compositionen
dc.subjectfat massen
dc.subjectheighten
dc.subjectR Medicineen
dc.subjectNational Institute for Health Research (NIHR)en
dc.subject13/53/03en
dc.subjectMedical Research Council (MRC)en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleActivin type I receptor polymorphisms and body composition in older individuals with sarcopenia – analyses from the LACE randomised controlled trialen
dc.typeJournal articleen

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