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Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)

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dc.contributor.authorClarke, T-K
dc.contributor.authorAdams, M J
dc.contributor.authorDavies, G
dc.contributor.authorHoward, D M
dc.contributor.authorHall, L S
dc.contributor.authorPadmanabhan, S
dc.contributor.authorMurray, A D
dc.contributor.authorSmith, B H
dc.contributor.authorCampbell, A
dc.contributor.authorHayward, C
dc.contributor.authorPorteous, D J
dc.contributor.authorDeary, I J
dc.contributor.authorMcIntosh, A M
dc.contributor.institutionUniversity of Aberdeen.Grampian Data Safe Haven (DaSH)en
dc.contributor.institutionUniversity of Aberdeen.Applied Medicineen
dc.contributor.institutionUniversity of Aberdeen.Aberdeen Biomedical Imaging Centreen
dc.date.accessioned2017-10-16T13:28:08Z
dc.date.available2017-10-16T13:28:08Z
dc.date.issued2017-10
dc.descriptionAcknowledgements This research has been conducted using the UK Biobank Resource: application number 4844. We are grateful to the families who took part in GS, the GPs and Scottish School of Primary Care for their help in recruiting them, and the whole GS team that includes academic researchers, clinic staff, laboratory technicians, clerical workers, IT staff, statisticians and research managers. Generation Scotland received core support from the Chief Scientist Office of the Scottish Government Health Directorates (CZD/16/6) and the Scottish Funding Council (HR03006). Genotyping of the GS samples was carried out by the Genetics Core Laboratory at the Wellcome Trust Clinical Research Facility, Edinburgh, Scotland, and was funded by the Medical Research Council UK and the Wellcome Trust (Wellcome Trust Strategic Award ‘STratifying Resilience and Depression Longitudinally’ (STRADL) Reference 104036/Z/14/Z). We acknowledge with gratitude the financial support received for this work from the Dr Mortimer and Theresa Sackler Foundation. DJP, IJD and AMM are members of The University of Edinburgh Centre for Cognitive Ageing and Cognitive Epidemiology, part of the cross council Lifelong Health and Wellbeing Initiative (MR/K026992/1). Funding from the Biotechnology and Biological Sciences Research Council and Medical Research Council is gratefully acknowledgeden
dc.description.statusPeer revieweden
dc.format.extent9
dc.format.extent556396
dc.identifier109991704
dc.identifier414a7cea-4af7-42a3-a406-beb1a9ca0701
dc.identifier28937693
dc.identifier85036511638
dc.identifier.citationClarke, T-K, Adams, M J, Davies, G, Howard, D M, Hall, L S, Padmanabhan, S, Murray, A D, Smith, B H, Campbell, A, Hayward, C, Porteous, D J, Deary, I J & McIntosh, A M 2017, 'Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)', Molecular Psychiatry, vol. 22, no. 10, pp. 1376-1384. https://doi.org/10.1038/mp.2017.153en
dc.identifier.doi10.1038/mp.2017.153
dc.identifier.iss10en
dc.identifier.issn1359-4184
dc.identifier.otherPubMedCentral: PMC5622124
dc.identifier.otherORCID: /0000-0003-4915-4847/work/44018547
dc.identifier.urihttp://hdl.handle.net/2164/9444
dc.identifier.vol22en
dc.language.isoeng
dc.relation.ispartofMolecular Psychiatryen
dc.subjectJournal Articleen
dc.subjectQH426 Geneticsen
dc.subjectChief Scientist Office (CSO)en
dc.subjectCZD/16/6en
dc.subjectBiotechnology and Biological Sciences Research Council (BBSRC)en
dc.subjectMedical Research Council (MRC)en
dc.subjectWellcome Trusten
dc.subject104036/Z/14/Zen
dc.subjectScottish Funding Councilen
dc.subjectHR03006en
dc.subject.lccQH426en
dc.titleGenome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)en
dc.typeJournal articleen

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