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Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity

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dc.contributor.authorPillon, Nicolas J.
dc.contributor.authorGabriel, Brendan M.
dc.contributor.authorDollet, Lucile
dc.contributor.authorSmith, Jonathon A. B.
dc.contributor.authorPuig, Laura Sardón
dc.contributor.authorBotella, Javier
dc.contributor.authorBishop, David J.
dc.contributor.authorKrook, Anna
dc.contributor.authorZierath, Juleen R.
dc.contributor.institutionUniversity of Aberdeen.Medical Sciencesen
dc.date.accessioned2020-06-18T15:15:00Z
dc.date.available2020-06-18T15:15:00Z
dc.date.issued2020-01-24
dc.descriptionThe authors are supported by grants from the Novo Nordisk Foundation (NNF14OC0011493, NNF17OC0030088 and NNF14OC0009941), Swedish Diabetes Foundation (DIA2018-357, DIA2018-336), Swedish Research Council (2015-00165, 2018-02389), the Strategic Research Program in Diabetes at Karolinska Institutet (2009-1068), the Stockholm County Council (SLL20150517, SLL20170159), the Swedish Research Council for Sport Science (P2018-0097), and the EFSD European Research Programme on New Targets for Type 2 Diabetes supported by an educational research grant from MSD. L.D. was supported by a Novo Nordisk postdoctoral fellowship run in partnership with Karolinska Institutet. B.M.G. was supported by a fellowship from the Wenner-Gren Foundation (Sweden). N.J.P. was supported by an Individual Fellowship from the Marie Skłodowska-Curie Actions (European Commission, 704978, 675610) and grants from the Sigurd och Elsa Goljes Minne and Lars Hiertas Minne Foundations (Sweden). D.J.B. was supported by the ANZ Mason Foundation and Australian Research Council Discovery Program (ARC DP140104165). Additional support was received from the Novo Nordisk Foundation Center for Basic Metabolic Research at the University of Copenhagen (NNF18CC0034900) (to J.R.Z.). We thank Dr. Nanjiang Shu from National Bioinformatics Infrastructure Sweden (NBIS) for setting up the web-server. We also thank EGI federated cloud for providing the computer resource for hosting the web-server. We acknowledge the Beta Cell in-vivo Imaging/Extracellular Flux Analysis core facility supported by the Strategic Research Program (SRP) in Diabetes for the usage of the Seahorse flux analyzer. Open access funding provided by Karolinska Institute.en
dc.description.statusPeer revieweden
dc.format.extent15
dc.format.extent3870298
dc.identifier171137069
dc.identifier59488d15-210b-442e-b549-a6ad7aee003b
dc.identifier000526550000001
dc.identifier31980607
dc.identifier85078120560
dc.identifier.citationPillon, N J, Gabriel, B M, Dollet, L, Smith, J A B, Puig, L S, Botella, J, Bishop, D J, Krook, A & Zierath, J R 2020, 'Transcriptomic profiling of skeletal muscle adaptations to exercise and inactivity', Nature Communications, vol. 11, 470. https://doi.org/10.1038/s41467-019-13869-wen
dc.identifier.doi10.1038/s41467-019-13869-w
dc.identifier.issn2041-1723
dc.identifier.otherORCID: /0000-0001-6878-8779/work/67813898
dc.identifier.urihttps://hdl.handle.net/2164/14526
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85078120560&partnerID=8YFLogxKen
dc.identifier.vol11en
dc.language.isoeng
dc.relation.ispartofNature Communicationsen
dc.subjectmolecular medicineen
dc.subjecttranslational researchen
dc.subjectHumansen
dc.subjectExercise/physiologyen
dc.subjectGene Expression Profilingen
dc.subjectGene Regulatory Networksen
dc.subjectReceptors, Steroid/geneticsen
dc.subjectResistance Trainingen
dc.subjectAdaptation, Physiological/geneticsen
dc.subjectReceptors, Thyroid Hormone/geneticsen
dc.subjectDNA-Binding Proteins/geneticsen
dc.subjectMuscle, Skeletal/physiologyen
dc.subjectGene Ontologyen
dc.subjectSedentary Behavioren
dc.subjectR Medicineen
dc.subjectEuropean Commissionen
dc.subject704978en
dc.subject675610en
dc.subjectSupplementary Dataen
dc.subject.lccRen
dc.titleTranscriptomic profiling of skeletal muscle adaptations to exercise and inactivityen
dc.typeJournal articleen

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