Mocciaro, GabrieleAllison, MichaelJenkins, BenjaminAzzu, VianHuang-Doran, IsabelHerrera-Marcos, Luis VicenteHall, ZoeMurgia, AntonioSusan, DaviesFrontini, MattiaVidal-Puig, AntonioKoulman, AlbertGriffin, Julian L.Vacca, Michele2023-05-172023-05-172023-07Mocciaro, G, Allison, M, Jenkins, B, Azzu, V, Huang-Doran, I, Herrera-Marcos, L V, Hall, Z, Murgia, A, Susan, D, Frontini, M, Vidal-Puig, A, Koulman, A, Griffin, J L & Vacca, M 2023, 'Non-alcoholic fatty liver disease is characterised by a reduced polyunsaturated fatty acid transport via free fatty acids and high-density lipoproteins (HDL)', Molecular Metabolism, vol. 73, 101728. https://doi.org/10.1016/j.molmet.2023.1017282212-8778ORCID: /0000-0003-1336-7744/work/135638911https://hdl.handle.net/2164/20745Funding Information: The cohort was initially generated with the support of the Evelyn Trust (to M.A.). G.M., Z.H., M.V., and J.L.G. were funded by the Medical Research Council (MRC) (Lipid Profiling and Signalling, MC UP A90 1006 & Lipid Dynamics and Regulation, MC PC 13030 to J.L.G.; MR/W019132/1 to Z.H.) . MV is supported by the University of Bari (Horizon Europe Seed cod. id. S06-miRNASH) , the Foundation for Liver Research (Intramural Funding) , Associazione Italiana Ricerca sul Cancro ( IG2022 Grant n. 27521 ) and Ministry of University and Research on Next Generation EU Funds ( Cod PE00000003 , CUP: H93C22000630001 , DD MUR 1550 , Title: “ON Foods - Research and innovation network on food and nutrition Sustainability, Safety and Security – Working ON Foods” ; Cod: CN00000041 , CUP: H93C22000430007 , Title PNRR “National Center for Gene Therapy and Drugs based on RNA Technology”, M4C2-Investimento 1.4 ; Code: CN00000013 , CUP: H93C22000450007 , Title PNRR: “National Centre for HPC, Big Data and Quantum Computing” ). G.M. was also partly funded by NIHR Cambridge Biomedical Research Centre and the Foundation for Liver Research . A.K. and B.J. are supported by the National Institute for Health Research Cambridge Biomedical Research Centre (IS-BRC-1215-20014). M.F. is funded by the British Heart Foundation (FS/18/53/33863) and is supported by the National Institute for Health and Care Research Exeter Biomedical Research Centre . The views expressed are those of the author(s) and not necessarily those of the funders (e.g. NIHR or the Department of Health and Social Care). V.A. was funded by the University of Cambridge , the Mason Medical Research Trust , the Academy of Medical Sciences and the NIHR Cambridge Biomedical Research Centre. Publisher Copyright: © 20231669425engSDG 3 - Good Health and Well-beingLC-MSLipidomicsLipoprotein metabolismNon-alcoholic fatty liver disease (NAFLD)ObesityR MedicineMolecular BiologyCell BiologyMedical Research Council (MRC)MR/W019132/1Supplementary InformationRJournal article10.1016/j.molmet.2023.101728http://www.scopus.com/inward/record.url?scp=85153881981&partnerID=8YFLogxK73