Bain, JudeAlonso, FernandaChilders, DelmaWalls, CatrionaMacKenzie, KevinPradhan, ArnabLewis, Leanne ELouw, JohannaAvelar, Gabriela MLarcombe, Daniel ENetea, Mihai G.Gow, Neil A.R.Brown, Gordon DErwig, LarsBrown, Alistair J.P.2021-04-062021-04-062021-04-13Bain, J, Alonso, F, Childers, D, Walls, C, MacKenzie, K, Pradhan, A, Lewis, L E, Louw, J, Avelar, G M, Larcombe, D E, Netea, M G, Gow, N A R, Brown, G D, Erwig, L & Brown, A J P 2021, 'Immune cells fold and damage fungal hyphae', PNAS, vol. 118, no. 15, e2020484118. https://doi.org/10.1073/pnas.20204841180027-8424ORCID: /0000-0002-0041-5375/work/91891875ORCID: /0000-0003-2869-7332/work/91891878ORCID: /0000-0002-1060-0419/work/112075829https://hdl.handle.net/2164/16191Acknowledgements We thank Ben Rutter and Alex Brand for providing Mycelia sterilia hyphae, and Gillian Griffiths for insightful advice. We are grateful to the Microscopy and Histology Core Facility at the University of Aberdeen for their help, advice and support. This work was funded by grants from the UK Medical Research Council [www.mrc.ac.uk], to AJPB, NARG, LPE, MN (MR/M026663/1, MR/M026663/2), and from the University of Aberdeen to AP, DL. The work was also supported by Wellcome [www.wellcome.ac.uk]: NARG, GDB, AJPB (097377); NARG (101873, 200208); and GDB (102705). Further support for this work was also provided by the Medical Research Council Centre for Medical Mycology (MR/N006364/1). MGN was supported by an ERC Advanced Grant (#833247) and a Spinoza grant of the Netherlands Organization for Scientific Research. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.81485867engMacrophagesfungal hyphaemechanical forceimmunological synapsepodosomescytoskeletonR MedicineMedical Research Council (MRC)MR/M026663/1MR/M026663/2MR/N006364/1European Research Council#833247Wellcome Trust097377101873200208102705Supplementary DataRJournal article10.1073/pnas.202048411811815