Mechanisms Underlying the Delayed Activation of the Cap1 Transcription Factor in Candida albicans following Combinatorial Oxidative and Cationic Stress Important for Phagocytic Potency

Kos, IaroslavaPatterson, MirandaZnaidi, SadriKaloriti, Despoinada Silva Dantas, AlessandraHerrero De Dios, Carmen Mariad'Enfert, ChristopheBrown, Alistair James PetersenQuinn, Janet2016-04-182016-04-182016-03-29Kos, I, Patterson, M, Znaidi, S, Kaloriti, D, da Silva Dantas, A, Herrero De Dios, C M, d'Enfert, C, Brown, A J P & Quinn, J 2016, 'Mechanisms Underlying the Delayed Activation of the Cap1 Transcription Factor in Candida albicans following Combinatorial Oxidative and Cationic Stress Important for Phagocytic Potency', mBio, vol. 7, no. 2, e00331-16. https://doi.org/10.1128/mBio.00331-16http://hdl.handle.net/2164/5876ACKNOWLEDGMENTS We are grateful to Brian Morgan and Elizabeth Veal for insightful discussions, Mélanie Ikeh for experimental assistance, and Scott Moye-Rowley (University of Iowa) for the gift of the anti-Cap1 antibody. This work was funded by the NIHR Newcastle Biomedical Research Centre (I.K.), a BBSRC DTG studentship (M.J.P.), the Wellcome Trust (grants 089930 and 097377 to J.Q. and 080088 and 097377 to A.J.P.B.), the BBSRC (grants BB/K016393/1 to J.Q. and BB/F00513X/1 and BB/K017365/1 to A.J.P.B.), the European Research Council (STRIFE Advanced grant ERC-2009-AdG-249793 to A.J.P.B.), the ANR (grant CANDIHUB, ANR-14-CE14-0018-01, to C.D.), and the French Government’s Investissement d’Avenir program (grant IBEID, ANR-10-LABX-62-IBEID, to C.D.). FUNDING INFORMATION This work, including the efforts of Alistair J.P. Brown, was funded by Wellcome Trust (097377 and 080088). This work, including the efforts of Janet Quinn, was funded by Wellcome Trust (097377 and 089930). This work, including the efforts of Alistair J.P. Brown, was funded by EC European Research Council (ERC) (ERC-2009-AdG-249793). This work, including the efforts of Alistair J.P. Brown, was funded by Biotechnology and Biological Sciences Research Council (BBSRC) (BB/F00513X/1 and BB/K017365/1). This work, including the efforts of Janet Quinn, was funded by Biotechnology and Biological Sciences Research Council (BBSRC) (BB/K016393/1). This work, including the efforts of Christophe d’Enfert, was funded by Agence Nationale de la Recherche (ANR) (ANR-14-CE14-0018-01 and ANR-10-LABX-62-IBEID).2919629engQR MicrobiologyBiotechnology and Biological Sciences Research Council (BBSRC)BB/F00513X/1BB/K017365/1Wellcome Trust097377089930080088QRMechanisms Underlying the Delayed Activation of the Cap1 Transcription Factor in Candida albicans following Combinatorial Oxidative and Cationic Stress Important for Phagocytic PotencyJournal article10.1128/mBio.00331-1672