Mapperley, Christophervan de Lagemaat, Louie NLawson, HannahTavosanis, AndreaParis, JasminCampos, JoanaWotherspoon, DavidDurko, JozefSarapuu, AnnikaChoe, JunhoIvanova, IvaylaKrause, Daniela Svon Kriegsheim, AlexMuch, ChristianMorgan, MarcosGregory, Richard IMead, Adam JO'Carroll, DónalKranc, Kamil R2023-09-272023-09-272021-03-01Mapperley, C, van de Lagemaat, L N, Lawson, H, Tavosanis, A, Paris, J, Campos, J, Wotherspoon, D, Durko, J, Sarapuu, A, Choe, J, Ivanova, I, Krause, D S, von Kriegsheim, A, Much, C, Morgan, M, Gregory, R I, Mead, A J, O'Carroll, D & Kranc, K R 2021, 'The mRNA m6A reader YTHDF2 suppresses proinflammatory pathways and sustains hematopoietic stem cell function', Journal of Experimental Medicine, vol. 218, no. 3, e20200829. https://doi.org/10.1084/jem.202008290022-1007PubMedCentral: PMC7653684ORCID: /0000-0002-2947-1557/work/143414080https://hdl.handle.net/2164/21771K.R. Kranc’s laboratory is funded by a Cancer Research UK program grant (C29967/A26787) and project grants from the Medical Research Council, Blood Cancer UK, Barts Charity, and the Kay Kendall Leukaemia Fund. This research was supported by Wellcome Trust funding to D. O’Carroll (106144) and the Wellcome Centre for Cell Biology (203149). Part of this work was carried out in the framework of the European Cooperation in Science and Technology EPITRAN CA16120. C. Mapperley is funded by a Wellcome Trust PhD studentship (108906/Z/15/Z).154928691engSDG 3 - Good Health and Well-beingAdenosine/analogs & derivativesAnimalsCell LineageCell ProliferationCellular SenescenceGene DeletionHematopoiesisHematopoietic Stem Cell TransplantationHematopoietic Stem Cells/metabolismInflammation/geneticsLymphocytes/metabolismMice, Inbred C57BLMyeloid Cells/metabolismRNA, Messenger/geneticsRNA-Binding Proteins/metabolismR Medicine (General)Cancer Research UKC29967/A26787Medical Research Council (MRC)Wellcome Trust106144203149108906/Z/15/ZSupplementary DataSupplementary InformationR1Journal article10.1084/jem.202008292183