Sterne, Jonathan ACHernán, Miguel AReeves, Barnaby CSavović, JelenaBerkman, Nancy DViswanathan, MeeraHenry, DavidAltman, Douglas GAnsari, Mohammed TBoutron, IsabelleCarpenter, James RChan, An-WenChurchill, RachelDeeks, Jonathan JHróbjartsson, AsbjørnKirkham, JamieJüni, PeterLoke, Yoon KPigott, Theresa DRamsay, Craig RRegidor, DeborahRothstein, Hannah RSandhu, LakhbirSantaguida, Pasqualina LSchünemann, Holger JShea, BeverlyShrier, IanTugwell, PeterTurner, LucyValentine, Jeffrey CWaddington, HughWaters, ElizabethWells, George AWhiting, Penny FHiggins, Julian Pt2017-01-302017-01-302016-10-12Sterne, J AC, Hernán, M A, Reeves, B C, Savović, J, Berkman, N D, Viswanathan, M, Henry, D, Altman, D G, Ansari, M T, Boutron, I, Carpenter, J R, Chan, A-W, Churchill, R, Deeks, J J, Hróbjartsson, A, Kirkham, J, Jüni, P, Loke, Y K, Pigott, T D, Ramsay, C R, Regidor, D, Rothstein, H R, Sandhu, L, Santaguida, P L, Schünemann, H J, Shea, B, Shrier, I, Tugwell, P, Turner, L, Valentine, J C, Waddington, H, Waters, E, Wells, G A, Whiting, P F & Higgins, J P 2016, 'ROBINS-I : a tool for assessing risk of bias in non-randomized studies of interventions', BMJ, vol. 355, i4919. https://doi.org/10.1136/bmj.i49190959-8146PubMedCentral: PMC5062054ORCID: /0000-0003-4043-7349/work/84131394http://hdl.handle.net/2164/8085Development of ROBINS-I was funded by a Methods Innovation Fund grant from Cochrane and Medical Research Council grant MR/M025209/1. Sterne and Higgins are members of the Medical Research Council Integrative Epidemiology Unit at the University of Bristol which is supported by the Medical Research Council and the University of Bristol (grant MC_UU_12013/9). This research was partly funded by NIH grant P01 CA134294. Sterne was supported by National Institute for Health Research Senior Investigator award NF-SI-0611-10168. Savović and Whiting were supported by National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care West (NIHR CLAHRC West). Reeves was supported by the National Institute for Health Research Bristol Biomedical Research Unit in Cardiovascular Disease. None of the funders had a role in the development of the ROBINS-I tool, although employees of Cochrane contributed to some of the meetings and workshops. The views expressed are those of the authors and not necessarily those of Cochrane, the NHS, the NIHR or the Department of Health.7322752engR MedicineMedical Research Council (MRC)MR/M025209/1MC_UU_12013/9National Institute for Health Research (NIHR)NF-SI-0611-10168Supplementary DataRJournal article10.1136/bmj.i4919355