Childers, Delma S.Raziunaite, IngridaMol Avelar, GabrielaMackie, JoannaBudge, SusanStead, DavidGow, Neil A. R.Lenardon, Megan D.Ballou, Elizabeth R.MacCallum, Donna M.Brown, Alistair J. P.2016-04-182016-04-182016-04-13Childers, D S, Raziunaite, I, Mol Avelar, G, Mackie, J, Budge, S, Stead, D, Gow, N A R, Lenardon, M D, Ballou, E R, MacCallum, D M & Brown, A J P 2016, 'The Rewiring of Ubiquitination Targets in a Pathogenic Yeast Promotes Metabolic Flexibility, Host Colonization and Virulence', PLoS Pathogens, vol. 12, no. 4, 1005566. https://doi.org/10.1371/journal.ppat.10055661553-7366ORCID: /0000-0003-4833-0378/work/47631094ORCID: /0000-0001-9268-5868/work/76974338ORCID: /0000-0003-2869-7332/work/76975985http://hdl.handle.net/2164/5870Funding: This work was funded by the European Research Council [http://erc.europa.eu/], AJPB (STRIFE Advanced Grant; C-2009-AdG-249793). The work was also supported by: the Wellcome Trust [www.wellcome.ac.uk], AJPB (080088, 097377); the UK Biotechnology and Biological Research Council [www.bbsrc.ac.uk], AJPB (BB/F00513X/1, BB/K017365/1); the CNPq-Brazil [http://cnpq.br], GMA (Science without Borders fellowship 202976/2014-9); and the National Centre for the Replacement, Refinement and Reduction of Animals in Research [www.nc3rs.org.uk], DMM (NC/K000306/1). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript. Acknowledgments We thank Dr. Elizabeth Johnson (Mycology Reference Laboratory, Bristol) for providing strains, and the Aberdeen Proteomics facility for the biotyping of S. cerevisiae clinical isolates, and to Euroscarf for providing S. cerevisiae strains and plasmids. We are grateful to our Microscopy Facility in the Institute of Medical Sciences for their expert help with the electron microscopy, and to our friends in the Aberdeen Fungal Group for insightful discussions.262507885engQR MicrobiologyWellcome Trust080088097377Biotechnology and Biological Sciences Research Council (BBSRC)BB/F00513X/1BB/K017365/1European Research CouncilC-2009-AdG-249793National Centre for the Replacement, Refinement and Reduction of Animals in Research (NC3R's)NC/K000306/1Supplementary DataQRJournal article10.1371/journal.ppat.1005566https://doi.org/10.1371/journal.ppat.1005566.s001https://doi.org/10.1371/journal.ppat.1005566.s002https://doi.org/10.1371/journal.ppat.1005566.s003https://doi.org/10.1371/journal.ppat.1005566.s004https://doi.org/10.1371/journal.ppat.1005566.s005https://doi.org/10.1371/journal.ppat.1005566.s006https://doi.org/10.1371/journal.ppat.1005566.s007https://doi.org/10.1371/journal.ppat.1005566.s008https://doi.org/10.1371/journal.ppat.1005566.s009124