Cook, Jonathan AMaclennan, Graeme SPalmer, TomLois, NoemiEmsley, Richard2018-03-162018-03-162018-04Cook, J A, Maclennan, G S, Palmer, T, Lois, N & Emsley, R 2018, 'Instrumental variable methods for a binary outcome were used to informatively address non-compliance in a randomised trial in surgery', Journal of Clinical Epidemiology, vol. 96, pp. 126-132. https://doi.org/10.1016/j.jclinepi.2017.11.0110895-4356ORCID: /0000-0002-1039-5646/work/98038549http://hdl.handle.net/2164/10185Open Access funded by Medical Research Council Acknowledgments: Jonathan Cook held an MRC personal fellowship (reference: G1002292) while some of this work was undertaken. The authors would like to thank the FILMS trial team (Noemi Lois, Jennifer Burr, John Norrie, Luke Vale, Jonathan Cook, Alison McDonald, Charles Boachie, Laura Ternent, and Gladys McPherson) and the FILMS study group (Hatem Atta, Stephen Beatty, Catherine Cleary, Andrew Dick, John Ellis, John Forrester, Carl Groenewald, Richard Haynes, Henrich Heimann, Muhammad Irfan Khan, Dara Kilmartin, Noemi Lois, John Murdoch, Asif Orakzai, CK Patel, Ian Pearce, Tarik Saddik, David Steel, David Wong, Charles Cottriall, Cherry Daly, Laura Duncan, Karon McEwing, Sarah Muir, Anita Murphy, Stan Keys, Lynda Lindsell, and Valerie Tompkin, Terri Ainley, Victor Beatty, Gillian Bennerson, Anne Bolton, Jon Brett, Alison Farrow, Ronnie Jackson, Tony Johnston, Marie Kinsella, Stephen Neilson, Hugh Nolan, Sarah Stanley, Jim Talbot, and Ayyakkawnu Manivannan) for the data set and Charles Boachie in particular for his previous analysis of the main data set. FILMS was funded by the Chief Scientist Office, Scotland (reference: CZH/4/235). The authors would like to thank the reviewers for helpful comments, which have improved the manuscript.7258770engJournal Articleinstrumental variableRCTnon-compliancebinarycausal modellingrisk ratioR MedicineMedical Research Council (MRC)G1002292Chief Scientist Office (CSO)CZH/4/235RJournal article10.1016/j.jclinepi.2017.11.01196