Burke, Luke K.Ogunnowo-Bada, EmmanuelGeorgescu, TeodoraCristiano, ClaudiaMartinez De Morentin, Pablo B.Valencia-Torres, LourdesD'Agostino, GiuseppeRiches, ChristineHeeley, NicholasRuan, YueRubinstein, MarceloLow, Malcolm J.Myers, Martin G.Rochford, Justin J.Evans, Mark L.Heisler, Lora K.2018-01-092018-01-092017-10-31Burke, L K, Ogunnowo-Bada, E, Georgescu, T, Cristiano, C, Martinez De Morentin, P B, Valencia-Torres, L, D'Agostino, G, Riches, C, Heeley, N, Ruan, Y, Rubinstein, M, Low, M J, Myers, M G, Rochford, J J, Evans, M L & Heisler, L K 2017, 'Lorcaserin improves glycemic control via a melanocortin neurocircuit', Molecular Metabolism, vol. 6, no. 10, pp. 1092-1102. https://doi.org/10.1016/j.molmet.2017.07.0042212-8778ORCID: /0000-0002-5020-4939/work/53729084http://hdl.handle.net/2164/9877Authors wish to thank members of staff of the Medical Research Facility University of Aberdeen, Ms Raffaella Chianese, Ms Pat Bain, Dr Samuel Virtue and Dr Guenievre Roussel for technical assistance. Work was supported by the Wellcome Trust (LKH: WT098012, WT081713; LKH/LKB: 093566/Z/10/A; JJR/GD'A/PBMM: 100574/Z/12/Z), Diabetes UK (MLE: 13/0004680), Biotechnology and Biological Sciences Research Council (LKH: BB/K001418/1, BB/NO17838/1 and JJR: BB/K017772/1), the Medical Research Council (JJR: MR/L002620/1; LKH: MC/PC/15077; GD'A: MR/P009824/1), the Cambridge MRC Centre for Study of Obesity and Related Disorders (MRC-CORD) to LKH, MLE and LKB, European Commission (PBMM/LKH 660219-NeuroEE), Genomics/Transcriptomics Core Facilities, the Neuroscience Graduate Program, the National Institutes of Health (MJL: DK066604; MJL/MR: DK068400; MGM: DK056731) and the Marilyn H. Vincent Foundation to MGM.113617617engSDG 3 - Good Health and Well-being5-HT2c receptorType 2 diabetesHypothalamusLorcaserinPro-opiomelanocortin (POMC)Melanocortin4 receptor (Mc4r)R Medicine (General)Wellcome TrustWT098012WT081713093566/Z/10/A100574/Z/12/ZBiotechnology and Biological Sciences Research Council (BBSRC)BB/K001418/1BB/NO17838/1BB/K017772/1Medical Research Council (MRC)MR/L002620/1MC/PC/15077MR/P009824/1European Commission660219-NeuroEESupplementary DataR1Journal article10.1016/j.molmet.2017.07.004610