Neerincx, AndreasHermann, ClemensAntrobus, Robinvan Hateren, AndyCao, HuanTrautwein, NicoStevanović, StefanElliott, TimDeane, Janet E.Boyle, Louise H.2017-06-072017-06-072017-04-20Neerincx, A, Hermann, C, Antrobus, R, van Hateren, A, Cao, H, Trautwein, N, Stevanović, S, Elliott, T, Deane, J E & Boyle, L H 2017, 'TAPBPR bridges UDP-glucose : glycoprotein glucosyltransferase 1 onto MHC class I to provide quality control in the antigen presentation pathway', eLife, vol. 6, e23049, pp. 1-25. https://doi.org/10.7554/eLife.23049http://hdl.handle.net/2164/8767Funding Wellcome: Senior Research Fellowship 104647, Andreas Neerincx, Louise H Boyle Royal Society: University Research Fellowship, UF100371, Janet E Deane Cancer Research UK: Programme Grant, C7056A, Andy van Hateren, Tim Elliott Deutsche Forschungsgemeinschaft: SFB 685, Nico Trautwein, Stefan Stevanović Wellcome: PhD studentship, 089563, Clemens Hermann Wellcome: Strategic Award 100140, Robin Antrobus Wellcome: Programme grant, WT094847MA, Huan Cao Acknowledgements We are extremely grateful to Peter Cresswell and Najla Arshad (Yale University School of Medicine, New Haven, CT) for valuable advice, tapasin and TAP-specific antibody reagents, and the recombinant calreticulin proteins. We thank John Trowsdale (University of Cambridge, UK) for his mentorship and critical reading of this manuscript, and Jim Kaufman (University of Cambridge, UK) for useful discussions. We also thank Yi Cao (Cranfield University, UK) for MATLAB programming for densitometry analysis, and Mark Vickers and Sadie Henderson (Scottish National Blood Transfusion Services, UK) for permitting the use of and assistance with the Amersham WB system. The reagent ARP7099 FEC peptide pool was obtained from the Centre for AIDS Reagents, National Institute for Biological Standards and Control (NIBSC), and was donated by the NIH AIDS Reagent Program, Division of AIDS, NIAID, NIH.251936505engSDG 3 - Good Health and Well-beingR Medicine (General)Wellcome Trust104647089563100140WT094847MACancer Research UKC7056AR1Journal article10.7554/eLife.230496