Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome

Xu, ZhengyaoThomas, LouiseDavies, BenChalmers, RonaldSmith, MaggieBrown, William2014-08-282014-08-282013-10-20Xu, Z, Thomas, L, Davies, B, Chalmers, R, Smith, M & Brown, W 2013, 'Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome', BMC Biotechnology, vol. 13, 87. https://doi.org/10.1186/1472-6750-13-871472-6750http://hdl.handle.net/2164/3390This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. This work was supported by BBSRC grant: BB/H005277/1; New recombinases for genome engineering.1439142engserine recombinasesgenome manipulationDNA damagesite-specific recombinationstreptomyces phage PHI-BT1PHI-C31 integrasemammalian-cellscassette exchangeexcisiondirectionalityprophageTP901-1systemT TechnologyTAccuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genomeJournal article10.1186/1472-6750-13-8713