Devereux, GrahamCotton, SeonaidhBarnes, PeterBriggs, AndrewBurns, GrahamChaudhuri, RekhaChrystyn, HenryDavies, LisaDe Soyza, AnthonyFielding, ShonaGompertz, SimonHaughney, John Andrew FrancisLee, Amanda JMcCormack, KirstyMcPherson, GladysMorice, AlynNorrie, JohnSullivan, AnitaWilson, AndrewPrice, David2015-07-272015-07-272015-06-10Devereux, G, Cotton, S, Barnes, P, Briggs, A, Burns, G, Chaudhuri, R, Chrystyn, H, Davies, L, De Soyza, A, Fielding, S, Gompertz, S, Haughney, J A F, Lee, A J, McCormack, K, McPherson, G, Morice, A, Norrie, J, Sullivan, A, Wilson, A & Price, D 2015, 'Use of low-dose oral theophylline as an adjunct to inhaled corticosteroids in preventing exacerbations of chronic obstructive pulmonary disease : study protocol for a randomised controlled trial', Trials, vol. 16, 267. https://doi.org/10.1186/s13063-015-0782-21745-6215ORCID: /0000-0002-4865-9061/work/159078137http://hdl.handle.net/2164/4707Acknowledgements This project is funded by the National Institute for Health Research Health Technology Assessment Programme (project number 11/58/15). The Uniphyllin MR tablets have been provided gratis by Napp Pharmaceuticals Limited. As a courtesy, Napp Pharmaceuticals Limited will be provided with a copy of any manuscript prior to submission. We would like to acknowledge Nicholas Locantore for providing us with detailed data from the ECLIPSE study.864755engCOPDtheophyllineinhaled corticosteroidsexacerbationrandomised controlled trialR MedicineNational Institute for Health Research (NIHR)RJournal article10.1186/s13063-015-0782-216