Tau Protein Phosphorylated at Threonine-231 Is Expressed Abundantly in the Cerebellum in Prion Encephalopathies

Gómez-López, Víctor ManuelViramontes-Pintos, AmparoOntiveros-Torres, Miguel AngelGarcés-Ramírez, LindaDe La Cruz-López, FidelVillanueva-Fierro, IgnacioBravo-Muñoz, MarelyHarrington, CharlesMartínez-Robles, SandraYescas, PetraGuadarrama-Ortíz, ParménidesHernandes-Alejandro, MarioMontiel-Sosa, José FranciscoPacheco-Herrero, MarLuna-Muñoz, José2021-07-202021-07-202021-05-18Gómez-López, V M, Viramontes-Pintos, A, Ontiveros-Torres, M A, Garcés-Ramírez, L, De La Cruz-López, F, Villanueva-Fierro, I, Bravo-Muñoz, M, Harrington, C, Martínez-Robles, S, Yescas, P, Guadarrama-Ortíz, P, Hernandes-Alejandro, M, Montiel-Sosa, J F, Pacheco-Herrero, M & Luna-Muñoz, J 2021, 'Tau Protein Phosphorylated at Threonine-231 Is Expressed Abundantly in the Cerebellum in Prion Encephalopathies', Journal of Alzheimer's Disease, vol. 81, no. 2, pp. 769-785. https://doi.org/10.3233/JAD-2013081387-2877ORCID: /0000-0003-2250-3920/work/173415871https://hdl.handle.net/2164/16838ACKNOWLEDGMENTS: The authors want to express their gratitude to the following: Dr. P. Davies † (Albert Einstein College of Medicine, Bronx, NY, USA) and Lester I. Binder † (North Western, Chicago, IL, USA) for the generous gift of mAbs TG-3 and Alz-50, and Tau-1, Tau-5 and Tau-7, respectively; Tec. Amparo Viramontes Pintos for the handling of the brain tissue; support in the confocal microscopy unit of CIIDIR Durango, Instituto Politécnico Nacional; Union Medica University Clinic, Dominican Republic, for their support and collaboration in the development of this research project. We also want to express our gratitude to the Mexican families who have donated the brain of their loved ones affected with Alzheimer's disease and made our research possible. This work is dedicated to the memory of Professor Dr. José Raúl Mena López †. †Deceased. This work was supported by Fondo Nacional de Ciencia y Tecnologia, FONDOCyT, from the Ministry of Higher Education, Science and Technology, Dominican Republic (2015-3A2-127 to MP-H) and (2018-2019-2A3-208 to JL-M and MP-H).1784796306engCerebellumneuronal deathprion encephalopathyprion proteintau proteinR MedicineRTau Protein Phosphorylated at Threonine-231 Is Expressed Abundantly in the Cerebellum in Prion EncephalopathiesJournal article10.3233/JAD-201308http://www.scopus.com/inward/record.url?scp=85106953972&partnerID=8YFLogxK812