Smith, Daniel LMitchell, Sharon EJohnson, Maria SGibbs, Victoria KDickinson, StephanieHenschel, BeateLi, RuiKaiser, Kathryn AChusyd, Daniella EBrown, Andrew WAllison, David BSpeakman, John RNagy, Tim R2024-10-112024-10-112024-10-01Smith, D L, Mitchell, S E, Johnson, M S, Gibbs, V K, Dickinson, S, Henschel, B, Li, R, Kaiser, K A, Chusyd, D E, Brown, A W, Allison, D B, Speakman, J R & Nagy, T R 2024, 'Benefits of calorie restriction in mice are mediated via energy imbalance, not absolute energy or protein intake', GeroScience, vol. 46, pp. 4809–4826. https://doi.org/10.1007/s11357-024-01166-42509-2723https://hdl.handle.net/2164/24383We thank Jifeng Huang and Xuemei Cao for their assistance with mouse care and data collection, the UAB Small Animal Phenotyping Core for body composition and indirect calorimetry measures, and the UAB Metabolism Core for hormone and metabolite assessments. We also acknowledge and thank the Biological Services Unit staff in Aberdeen for their help with animal care in facilities at the University of Aberdeen.185703413engLongevityAgingAmbient temperatureThermoneutralCalorie restrictionBody CompositionQP PhysiologySupplementary DataQPJournal article10.1007/s11357-024-01166-446