Pyle, MelissaBroome, Matthew RJoyce, EmmelineMacLennan, GraemeNorrie, JohnFreeman, DanielFowler, DavidHaddad, Peter MShiers, DavidHollis, ChrisSmith, JoLiew, AshleyByrne, Rory EFrench, PaulPeters, SarahHudson, JemmaDavies, LindaEmsley, RichardYung, AlisonBirchwood, MaxLongden, EleanorMorrison, Anthony P2019-07-192019-07-192019-07-04Pyle, M, Broome, M R, Joyce, E, MacLennan, G, Norrie, J, Freeman, D, Fowler, D, Haddad, P M, Shiers, D, Hollis, C, Smith, J, Liew, A, Byrne, R E, French, P, Peters, S, Hudson, J, Davies, L, Emsley, R, Yung, A, Birchwood, M, Longden, E & Morrison, A P 2019, 'Study protocol for a randomised controlled trial of CBT vs antipsychotics vs both in 14-18-year-olds : Managing Adolescent first episode Psychosis: a feasibility study (MAPS)', Trials, vol. 20, 395. https://doi.org/10.1186/s13063-019-3506-11745-6215Mendeley: 85cfdf96-671f-3cb0-99d3-5566490fe4cbORCID: /0000-0002-1039-5646/work/98038516http://hdl.handle.net/2164/12603Acknowledgements Thank you to all the participants, family members/carers who agreed to take part in the trial and clinicians who have supported participant enrolment into the trial. This study was supported by the National Institute for Health Research (NIHR), the NIHR MindTech MedTech Co-operative, the NIHR Nottingham Biomedical Research Centre and the Clinical Research Network-Mental Health. MBi is part funded by NIHR CLAHRC West Midlands. We are grateful to the Psychosis Research Unit (PRU) Service User Reference Group (SURG) for their consultation regarding the design of the study and contribution to the developments of study-related materials. We are grateful to our Independent Trial Steering Committee and Independent Data Monitoring Committee for providing oversight of the trial. Funding MAPS was funded by the NIHR HTA programme (project number 15/31/04) and the final report will be published in Health Technology Assessment. Visit the HTA programme website for further project information. The Sponsor is Greater Manchester Mental Health NHS Foundation Trust, email R&D@gmmh.nhs.uk. The views and opinions expressed therein are those of the authors and do not necessarily reflect those of the HTA programme, NIHR, NHS or the Department of Health. Authors’ contributions MP made substantial contribution to the development of the trial protocol and to the overall management of the trial and data management, and wrote the first draft of the manuscript. AL, AY, CH, DFo, DFr, DS, EL, LD, PF, SP, MBi, MBr and REB contributed to the application for funding, made substantial contribution to the design of the trial and protocol and critically read the manuscript. EJ contributed to the writing of the manuscript. GM made substantial contribution to the design of the trial, the protocol and the statistical analysis plan and critically read the manuscript. JN, RE contributed to the application for funding, made substantial contribution to the design of the trial, the protocol and the statistical analysis plan and critically read the manuscript. PH made substantial contribution to the design of the trial and protocol and critically read the manuscript. JS made a substantial contribution to the family intervention component of the protocol, provided FI supervision to therapists on the trial and contributed to the writing of the manuscript. JH made substantial contribution to the statistical analysis plan and critically read the manuscript. APM planned the study, contributed to the application for funding, made substantial contribution to the design of the trial protocol and the statistical analysis plan, managed the stud, and critically read the manuscript. All authors read and approved the final manuscript.795588engSDG 3 - Good Health and Well-beingCBTantipsychoticspsychosisAdolescent psychosisFamily interventionRandomised controlled trialSchizophreniaFirst-episode psychosisCognitive behavioural therapyPsychological interventionAntipsychotic medicationR MedicinePharmacology (medical)Medicine (miscellaneous)National Institute for Health Research (NIHR)NIHR HTA 15/31/04NIHR MindTech MedTech Co-operativeNIHR Nottingham Biomedical Research CentreClinical Research Network-Mental HealtNIHR CLAHRC West MidlandsRJournal article10.1186/s13063-019-3506-1http://www.scopus.com/inward/record.url?scp=85068571686&partnerID=8YFLogxKhttps://trialsjournal.biomedcentral.com/articles/10.1186/s13063-019-3506-1http://www.mendeley.com/research/study-protocol-randomised-controlled-trial-cbt-vs-antipsychotics-vs-both-1418yearolds-managing-adole20