Rudan, IgorMillington, TristanAntal, KarenGrange, ZoeFenton, LyndaSullivan, ChristopherBuelo, AudreyWood, RachaelWoolford, LanaSwann, Olivia V.Murray, Josephine L.K.Cullen, Lucy A.Moore, EmilyHaider, FasihAlmaghrabi, FatimaMcMenamin, JimAgrawal, UtkarshShah, Syed AhmarKerr, StevenSimpson, Colin R.Katikireddi, Srinivasa VittalRitchie, Sir Lewis D.Robertson, ChrisSheikh, Sir Aziz2022-09-282022-09-282022-12Rudan, I, Millington, T, Antal, K, Grange, Z, Fenton, L, Sullivan, C, Buelo, A, Wood, R, Woolford, L, Swann, O V, Murray, J L K, Cullen, L A, Moore, E, Haider, F, Almaghrabi, F, McMenamin, J, Agrawal, U, Shah, S A, Kerr, S, Simpson, C R, Katikireddi, S V, Ritchie, S L D, Robertson, C & Sheikh, S A 2022, 'BNT162b2 COVID-19 vaccination uptake, safety, effectiveness and waning in children and young people aged 12–17 years in Scotland', The Lancet Regional Health - Europe, vol. 23, 100513. https://doi.org/10.1016/j.lanepe.2022.1005132666-7762RIS: urn:76913292C54E98933C4D0808040B4145https://hdl.handle.net/2164/19244This study is part of the EAVE II project. EAVE II is funded by the MRC (MC_PC_19075) with the support of BREATHE—The Health Data Research Hub for Respiratory Health (MC_PC_19004), which is funded through the UK Research and Innovation Industrial Strategy Challenge Fund and delivered through the Health Data Research UK. This research is part of the Data and Connectivity National Core Study, led by Health Data Research UK in partnership with the Office for National Statistics and funded by UK Research and Innovation (grant ref MC_PC_20058). This work was also supported by The Alan Turing Institute via ‘Towards Turing 2.0’ EPSRC Grant Funding. Additional support has been provided through Public Health Scotland, the Scottish Government Director-General Health and Social Care and the University of Edinburgh. The original EAVE project was funded by the National Institute for Health Research (NIHR) Health Technology Assessment programme (11/46/23). The views expressed are those of the authors and not necessarily those of the NIHR, the Department of Health and Social Care, or the UK government. We thank Dave Kelly from Albasoft (Inverness, UK) for his support with making primary care data available, and Wendy Inglis-Humphrey, Vicky Hammersley, and Laura Brook (University of Edinburgh, Edinburgh, UK) for their support with project management and administration.16550150engSDG 3 - Good Health and Well-beingSDG 9 - Industry, Innovation, and InfrastructureCOVID-19BNT162b2 COVID-19 vaccinationVaccine uptakeVaccine safetyVaccine effectivenessVaccine waningChildren and young peopleAge group 12-15 yearsAge group 16-17 yearsScotlandUnited KingdomNational prospective cohort studyR MedicineMedical Research Council (MRC)Supplementary DataMC_PC_19075MC_PC_20058RJournal article10.1016/j.lanepe.2022.10051323